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74例严重阻塞性慢性呼吸功能不全患者(动脉血二氧化碳分压大于50托)接受间歇通气支持一年以上的长期结果(作者译)

[Long-term results of intermittent ventilatory assistance for 74 severe obstructive chronic respiratory insufficient patients (PaCO2 greater than 50 Torr) ventilated for more than a year (author's transl)].

作者信息

Muir J F, Hermant A, Laroche D, Lévi-Valensi P, Duwoos H

出版信息

Rev Fr Mal Respir. 1979 Jul-Aug;7(4):421-3.

PMID:398567
Abstract

From 1967 to 1978, home assisted ventilation (HAD) was applied to 74 severe chronic respiratory insufficient patients (67 COPD-7 restrictive). These patients used volume generators through mouth piece, except 3 of them who had a tracheostomy. The main results of this study are a highly statistically significant decrement (P less than 0,001) of the hospitalization durations and of the frequency of ARF, as well as an improvement of the survival duration in front of a non-tested group, and a significant decrease of haematocrit (less than 0,05) and P.V.R. (P less than 0,01). But blood gases and functional tests are not statistically different. Age (greater than 55 years) and delay after first ARF (greater than 2 years) when starting HAD are considered as pejorative factors.

摘要

1967年至1978年期间,对74例严重慢性呼吸功能不全患者(67例慢性阻塞性肺疾病患者,7例限制性肺疾病患者)应用了家庭辅助通气(HAD)。这些患者通过口含器使用容积发生器,其中3例患者进行了气管造口术。本研究的主要结果是住院时间和急性呼吸衰竭(ARF)频率在统计学上有高度显著下降(P<0.001),与未进行测试的组相比,生存时间有所改善,血细胞比容(P<0.05)和肺血管阻力(P<0.01)显著降低。但血气和功能测试在统计学上无差异。开始进行家庭辅助通气时的年龄(大于55岁)和首次急性呼吸衰竭后的延迟时间(大于2年)被视为不利因素。

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