Astle W F, Rosenbaum A L
Arch Ophthalmol. 1985 Apr;103(4):532-5. doi: 10.1001/archopht.1985.01050040074021.
Few reports of hereditary transmission patterns in congenital superior oblique palsy have been made in the past. In this study, three families with congenital superior oblique palsies have been identified and examined. Two members of each family had a superior oblique palsy. After full history, eye examination, and sensory testing, the patterns in each family have been analyzed. Deviations varied from binocular fusion and orthophoria to large vertical deviations, especially in adduction. Sensory patterns were compatible with the congenital nature of the palsy. A discussion of possible causes for a congenital superior oblique palsy is offered and the congenital superior oblique palsies are analyzed. A definite genetic transmission pattern could not be found, but possible explanations are considered. Regardless of etiology, therapy for this problem is unchanged from that for all superior oblique palsies. Occurrences of congenital trochlear palsies in multiple family members should be considered when a patient with this problem is diagnosed.
过去关于先天性上斜肌麻痹遗传传递模式的报道很少。在本研究中，已识别并检查了三个患有先天性上斜肌麻痹的家庭。每个家庭中有两名成员患有上斜肌麻痹。在完成全面病史、眼部检查和感觉测试后，对每个家庭的模式进行了分析。斜视程度从双眼融合和正视到明显的垂直斜视不等，尤其是在内收时。感觉模式与麻痹的先天性特征相符。本文讨论了先天性上斜肌麻痹的可能病因，并对先天性上斜肌麻痹进行了分析。虽然未发现明确的遗传传递模式，但考虑了可能的解释。无论病因如何，该问题的治疗方法与所有上斜肌麻痹的治疗方法相同。当诊断出患有此问题的患者时，应考虑多个家庭成员出现先天性滑车神经麻痹的情况。
