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作为局部用化妆品的含巴西坚果果肉油乳液

Pequi Pulp () Oil-Loaded Emulsions as Cosmetic Products for Topical Use.

作者信息

Pereira Tácio Fragoso, Borchardt Huelinton, Wanderley Wvandson F, Vasconcelos Ulrich, Leite Itamara F

机构信息

Programa de Pós-Graduação em Ciência e Engenharia de Materiais, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, Brazil.

Graduação em Biotecnologia, Centro de Biotecnologia, Universidade Federal da Paraíba, João Pessoa 58051-900, PB, Brazil.

出版信息

Polymers (Basel). 2025 Jan 17;17(2):226. doi: 10.3390/polym17020226.

Abstract

The pequi () is a typical fruit from the Brazilian Cerrado. From it, pequi pulp oil is extracted, a valuable product for cosmetic applications due to its high levels of unsaturated fatty acids and carotenoids. Carotenoids are antioxidant compounds that are easily oxidized. To improve pulp stability, emulsification techniques with carboxymethylcellulose at 1% (/) were used to encapsulate the pequi pulp oil at 1, 3, 5% (/), and 8% (/) of polysorbate 80 using a high-rotation mechanical stirrer. The pequi pulp oil was first characterized by FTIR and GC-MS. The results indicated the presence of chemical groups characteristic of the oil itself and the presence of a large proportion of fatty acids, which are essential for the maintenance of cutaneous hydration and the barrier, also acting in the tissue repair process. All emulsions presented stable over 120 days with slightly acidic pH values and were compatible with human skin. The droplet diameter was less than 330 nm, and the polydispersity index was around 0.3, indicating systems with low polydispersity. The Zeta potential (ζ) exhibited negative values sufficient to stabilize the emulsified systems. All emulsions behaved as non-Newtonian fluids, presenting pseudo-plastic and thixotropic properties that are considered important for topical applications.

摘要

佩基果()是一种源自巴西塞拉多的典型水果。从佩基果中提取出佩基果肉油,由于其富含不饱和脂肪酸和类胡萝卜素,是一种用于化妆品应用的宝贵产品。类胡萝卜素是易被氧化的抗氧化化合物。为提高果肉稳定性,使用1%(/)的羧甲基纤维素乳化技术,以1%、3%、5%(/)和8%(/)的聚山梨醇酯80对佩基果肉油进行包封,采用高转速机械搅拌器。首先通过傅里叶变换红外光谱(FTIR)和气相色谱 - 质谱联用(GC - MS)对佩基果肉油进行表征。结果表明存在该油本身特有的化学基团以及大量脂肪酸,这些脂肪酸对于维持皮肤水合作用和屏障至关重要,在组织修复过程中也发挥作用。所有乳液在120天内保持稳定,pH值呈微酸性,且与人体皮肤相容。液滴直径小于330纳米,多分散指数约为0.3,表明体系具有低多分散性。zeta电位(ζ)呈现出足以稳定乳化体系的负值。所有乳液表现为非牛顿流体,具有假塑性和触变性,这些特性对于局部应用而言被认为很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7fbc/11768242/679e1c5192cf/polymers-17-00226-g001.jpg

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