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前瞻性队列研究中坚持地中海饮食与新发肌肉减少症之间的关联

Associations Between Adherence to the Mediterranean Diet and Incident Sarcopenia in Prospective Cohort Studies.

作者信息

Dominguez Ligia J, Veronese Nicola, Smith Lee, Ragusa Francesco Saverio, Schirò Piero, Di Bella Giovanna, Barbagallo Mario

机构信息

Department of Medicine and Surgery, "Kore" University of Enna, 94100 Enna, Italy.

Geriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, 90127 Palermo, Italy.

出版信息

Nutrients. 2025 Jan 16;17(2):313. doi: 10.3390/nu17020313.

Abstract

The loss of skeletal muscle mass and strength, known as sarcopenia, is prevalent in older adults and linked to an increased risk of disability, frailty, and early mortality. Muscle health is crucial for the functionality and independence of older adults. As the aging population continuously grows, finding cost-effective strategies for preventing and treating sarcopenia is an important public health priority. While nutrition is recognized as a key factor in the development of sarcopenia, its role in preventing and treating the condition is still under investigation. In recent decades, nutritional research has shifted from a focus on individual nutrients or healthy foods to examining the combination of nutrients and foods in dietary patterns, along with their potential synergistic and antagonistic effects. A balanced diet and regular participation in physical activity are essential for maintaining musculoskeletal health. One of the healthy eating patterns with the greatest evidence of multiple health benefits is the Mediterranean diet, which has also been linked to positive effects on muscle function in observational studies. However, there is a lack of intervention studies. This review explores the updated evidence from longitudinal prospective studies on associations between adherence to the Mediterranean diet and sarcopenia in order to promote preventive and intervention strategies for healthy muscle aging.

摘要

骨骼肌质量和力量的丧失,即肌肉减少症,在老年人中很普遍,并且与残疾、身体虚弱和过早死亡的风险增加有关。肌肉健康对老年人的功能和独立性至关重要。随着老龄化人口的持续增长,寻找具有成本效益的预防和治疗肌肉减少症的策略是一项重要的公共卫生优先事项。虽然营养被认为是肌肉减少症发生发展的一个关键因素,但其在预防和治疗该病症中的作用仍在研究中。近几十年来,营养研究已从关注单一营养素或健康食品,转向研究饮食模式中营养素和食物的组合,以及它们潜在的协同和拮抗作用。均衡饮食和定期参加体育活动对于维持肌肉骨骼健康至关重要。有最充分证据表明具有多种健康益处的健康饮食模式之一是地中海饮食,在观察性研究中,它也与对肌肉功能的积极影响有关。然而,缺乏干预性研究。本综述探讨了关于坚持地中海饮食与肌肉减少症之间关联的纵向前瞻性研究的最新证据,以促进健康肌肉衰老的预防和干预策略。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dc7e/11768633/a4ae881fbf4e/nutrients-17-00313-g001.jpg

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