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本文引用的文献

1
Inverted HA-EV immunization elicits stalk-specific influenza immunity and cross-protection in mice.倒置的血凝素-外泌体免疫在小鼠中引发茎特异性流感免疫和交叉保护。
Mol Ther. 2025 Feb 5;33(2):485-498. doi: 10.1016/j.ymthe.2024.12.052. Epub 2024 Dec 30.
2
Targeting Th17 cells: a promising strategy to treat oral mucosal inflammatory diseases.靶向Th17细胞：治疗口腔黏膜炎症性疾病的一种有前景的策略。
Front Immunol. 2023 Jul 26;14:1236856. doi: 10.3389/fimmu.2023.1236856. eCollection 2023.
3
Mucosal immune responses to infection and vaccination in the respiratory tract.呼吸道感染和疫苗接种的黏膜免疫应答。
Immunity. 2022 May 10;55(5):749-780. doi: 10.1016/j.immuni.2022.04.013.
4
The evolution and future of influenza pandemic preparedness.流感大流行防范的演变和未来。
Exp Mol Med. 2021 May;53(5):737-749. doi: 10.1038/s12276-021-00603-0. Epub 2021 May 6.
5
Small extracellular vesicles (sEVs): discovery, functions, applications, detection methods and various engineered forms.小细胞外囊泡（sEVs）：发现、功能、应用、检测方法及各种工程化形式
Expert Opin Biol Ther. 2021 Mar;21(3):371-394. doi: 10.1080/14712598.2021.1825677. Epub 2020 Sep 29.
6
Age-specific differences in the dynamics of protective immunity to influenza.流感保护性免疫的动态在年龄特异性方面的差异。
Nat Commun. 2019 Apr 10;10(1):1660. doi: 10.1038/s41467-019-09652-6.
7
How single mutations affect viral escape from broad and narrow antibodies to H1 influenza hemagglutinin.单突变如何影响 H1 流感血凝素对广谱和窄谱抗体的病毒逃逸。
Nat Commun. 2018 Apr 11;9(1):1386. doi: 10.1038/s41467-018-03665-3.
8
Neonatal mice possess two phenotypically and functionally distinct lung-migratory CD103 dendritic cell populations following respiratory infection.新生鼠在呼吸道感染后，肺部有两种表型和功能不同的 CD103 树突状细胞群迁移。
Mucosal Immunol. 2018 Jan;11(1):186-198. doi: 10.1038/mi.2017.28. Epub 2017 Apr 5.
9
Guiding the immune response against influenza virus hemagglutinin toward the conserved stalk domain by hyperglycosylation of the globular head domain.通过球状头部结构域的高糖基化引导针对流感病毒血凝素的免疫反应朝向保守的茎部结构域。
J Virol. 2014 Jan;88(1):699-704. doi: 10.1128/JVI.02608-13. Epub 2013 Oct 23.
10
Oral vaccination with inactivated influenza vaccine induces cross-protective immunity.口服接种灭活流感疫苗可诱导交叉保护免疫。
Vaccine. 2012 Jan 5;30(2):180-8. doi: 10.1016/j.vaccine.2011.11.028. Epub 2011 Nov 19.

A path toward developing a universal mucosal influenza vaccine: An upside-down influenza HA vaccine based on extracellular vesicles.

作者信息

Nejabat Sajjad, Adloo Zahra, Nezafat Navid

机构信息

Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran; Department of Pharmaceutical Biotechnology, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.

出版信息

Mol Ther. 2025 Feb 5;33(2):432-434. doi: 10.1016/j.ymthe.2025.01.003. Epub 2025 Jan 24.

DOI:10.1016/j.ymthe.2025.01.003
PMID:39862863
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11852659/
Abstract
摘要