Veltri Carlo, Albrecht Katinka, Kiltz Uta, Meyer-Olson Dirk, Späthling Susanna, Strangfeld Anja, Thiele Katja, Callhoff Johanna
Epidemiology and Health Services Research, German Rheumatology Research Center, Berlin, Germany
Epidemiology and Health Services Research, German Rheumatology Research Center, Berlin, Germany.
RMD Open. 2025 Jan 25;11(1):e004980. doi: 10.1136/rmdopen-2024-004980.
To analyse work participation among patients with inflammatory rheumatic musculoskeletal diseases (iRMDs), namely rheumatoid arthritis (RA), axial spondyloarthritis (axSpA), psoriatic arthritis (PsA), systemic lupus erythematosus (SLE), systemic sclerosis (SSc) and ANCA-associated vasculitis (AAV).
A cross-sectional sample of 16 421 patients from the National Database of the German Collaborative Arthritis Centers, aged <65 years were analysed. For each diagnosis, yearly rates of absenteeism, employment and disability pensions were analysed from 2010 to 2022. Population data were used to calculate standardised employment ratios (SERs), adjusted for age, sex, federal state and vocational qualification. The analysis was additionally stratified by sex, adjusting for other factors.
Over the observed time span, large employment increases were found across all diagnoses, namely in RA (54%-68%), PsA (58%-72%), SSc (47%-66%), AAV (43%-61%), SLE (48%-60%) and axSpA (65%-73%). SERs were for RA 0.88 (95% CI 0.86 to 0.90), axSpA (0.88 (0.84 to 0.91)), PsA (0.88 (0.85 to 0.91)), SSc (0.83 (0.75 to 0.91)), SLE (0.76 (0.72 to 0.80)) and AAV (0.73 (0.63 to 0.83)). In RA, axSpA, PsA and AAV, SERs were higher in men while in SLE and SSc men had lower SER. Median of yearly absenteeism due to the disease decreased by 5 (RA), 1 (axSpA), 6 (PsA), 11 (SLE), 4 (SSc) and 10 days (AAV) in the time span. Except for SSc, the proportion of disability pension receivers decreased for all diagnoses.
Since 2010, work participation has improved for patients with iRMDs, as reflected in higher employment, reduced absenteeism and less disability retirement. However, patients have not reached population employment rates.
分析炎症性风湿性肌肉骨骼疾病（iRMDs）患者的工作参与情况，这些疾病包括类风湿关节炎（RA）、轴性脊柱关节炎（axSpA）、银屑病关节炎（PsA）、系统性红斑狼疮（SLE）、系统性硬化症（SSc）和抗中性粒细胞胞浆抗体相关性血管炎（AAV）。
对德国协作关节炎中心国家数据库中16421名年龄小于65岁的患者进行横断面抽样分析。对于每种诊断，分析了2010年至2022年的年缺勤率、就业率和残疾抚恤金率。使用人口数据计算标准化就业比率（SERs），并根据年龄、性别、联邦州和职业资格进行调整。分析还按性别分层，并对其他因素进行调整。
在观察期内，所有诊断的就业率均大幅上升，RA（54%-68%）、PsA（58%-72%）、SSc（47%-66%）、AAV（43%-61%）、SLE（48%-60%）和axSpA（65%-73%）。RA的SERs为0.88（95%CI 0.86至0.90），axSpA为0.88（0.84至0.91），PsA为0.88（0.85至0.91），SSc为0.83（0.75至0.91），SLE为0.76（0.72至0.80），AAV为0.73（0.63至0.83）。在RA、axSpA、PsA和AAV中，男性的SERs较高，而在SLE和SSc中，男性的SERs较低。在该时间段内，因疾病导致的年缺勤中位数在RA中减少了5天，axSpA中减少了1天，PsA中减少了6天，SLE中减少了11天，SSc中减少了4天，AAV中减少了10天。除SSc外，所有诊断的残疾抚恤金领取者比例均下降。
自2010年以来，iRMDs患者的工作参与情况有所改善，表现为就业率提高、缺勤率降低和残疾退休人数减少。然而，患者尚未达到总体就业率。
