Latenkov V P
Biull Eksp Biol Med. 1985 Mar;99(3):344-6.
Circadian rhythms of adrenaline and noradrenaline excretion with urine in health and during 3 days after a single intake of 40 degrees alcohol from 5 to 6 p.m. in a dose of 6.2 ml/kg bw were examined in 20 healthy male volunteers aged 20 to 26 years, in spring. The data obtained were processed according to the "cosinor" program. Alcohol intake resulted in the tension of the sympathoadrenal system, with that tension being observed over 2 days and not removed after ethanol elimination. Circadian rhythms of catecholamine excretion essentially changed. Within the first day after alcohol intake, mesor and rhythm amplitudes increased, acrophases displaced for a time following alcoholization. By the second day the increase of the mesors was preserved, the acrophases returned to normal. Complete recovery of the normal circadian time structure took place during the third circadian cycle after alcohol intake.
在春季，对20名年龄在20至26岁的健康男性志愿者进行了研究，检测他们在健康状态下以及下午5点至6点单次摄入剂量为6.2毫升/千克体重的40度酒精后3天内尿中肾上腺素和去甲肾上腺素的昼夜节律。所获数据依据“余弦分析”程序进行处理。酒精摄入导致交感肾上腺系统紧张，这种紧张状态持续2天，且在乙醇消除后仍未消除。儿茶酚胺排泄的昼夜节律发生了本质变化。饮酒后的第一天内，中值和节律幅度增加，峰相位在饮酒后一度偏移。到第二天，中值的增加得以保持，峰相位恢复正常。饮酒后第三个昼夜周期内，正常的昼夜时间结构完全恢复。
