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推进印度的结核病消除工作:对结核病预防性治疗的当前策略及改进领域的定性综述

Advancing tuberculosis elimination in India: A qualitative review of current strategies and areas for improvement in tuberculosis preventive treatment.

作者信息

Shah Harsh, Patel Jay, Rai Sandeep, Sen Abhishek

机构信息

Department of Public Health Science, Indian Institute of Public Health Gandhinagar (IIPHG), Gandhinagar, India.

出版信息

IJID Reg. 2024 Dec 21;14:100556. doi: 10.1016/j.ijregi.2024.100556. eCollection 2025 Mar.

Abstract

Tuberculosis (TB), caused by , remains a global health challenge, despite being preventable and curable. The global goal to end TB by 2030, with India targeting a 90% reduction in TB incidence by 2025, demands comprehensive interventions in prevention, early detection, treatment, and capacity building. This study analyzes the 2023 Global TB Reports, published articles, guidelines, and data to explore India's current TB landscape. Despite progress in diagnostics and TB preventive treatment, significant challenges persist in accessibility, adherence, and treatment completion. Although advancements in household contact screening and TB preventive treatment initiation are notable, gaps in reporting, diagnostic algorithms, and adherence remain. Innovative diagnostic tools and shorter treatment regimens show promise but require more comprehensive implementation. India's strategy for TB elimination focuses on policy expansion, community engagement, and system enhancements. Continuous innovation, rigorous evaluation, and collaborative efforts are crucial to overcoming challenges and meeting TB elimination targets.

摘要

由[未提及具体病因]引起的结核病(TB)仍然是一项全球性的健康挑战,尽管它是可预防和可治愈的。到2030年终结结核病的全球目标,以及印度到2025年将结核病发病率降低90%的目标,都需要在预防、早期检测、治疗和能力建设方面采取全面干预措施。本研究分析了2023年《全球结核病报告》、已发表的文章、指南和数据,以探索印度当前的结核病状况。尽管在诊断和结核病预防性治疗方面取得了进展,但在可及性、依从性和治疗完成方面仍存在重大挑战。虽然家庭接触者筛查和结核病预防性治疗启动方面的进展值得注意,但在报告、诊断算法和依从性方面仍存在差距。创新的诊断工具和更短的治疗方案显示出前景,但需要更全面的实施。印度消除结核病的战略侧重于政策扩展、社区参与和系统强化。持续创新、严格评估和协作努力对于克服挑战和实现结核病消除目标至关重要。

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