Yamashita Kaoru, Yoshimine Shusei, Uto Akari, Uchino Minako, Kibe Toshiro, Sugimura Mitsutaka
Department of Dental Anesthesiology, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, JPN.
Department of Oral and Maxillofacial Surgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, JPN.
Cureus. 2024 Dec 24;16(12):e76345. doi: 10.7759/cureus.76345. eCollection 2024 Dec.
Imbalanced autonomic nervous system (ANS) activity raises concerns about the development of systemic complications during dental treatment. The purpose of this study was to determine whether a psychological test (Toho Medical Index (TMI)) prior to the impacted mandibular third molar extraction can identify patients with potentially imbalanced autonomic function.
In this prospective study, 34 healthy adult patients with no history of systemic disease were assigned to either the autonomic imbalance group (type II, III, IV) or the control group (type I) based on the results of the TMI. We evaluated sympathetic nervous system activity (low/high frequency (LF/HF)), parasympathetic nervous activity, heart rate (HR), and systolic blood pressure (SBP) values before extraction of the impacted mandibular third molar.
LF/HF and SBP in the autonomic imbalance group were significantly higher preoperatively than those in the control group. In addition, preoperative HF values were significantly lower in the autonomic imbalance group compared to those in controls (Mann-Whitney U test, p < 0.05); no significant group differences in HR were found (Mann-Whitney U test, p < 0.05).
ANS activity before extraction of the impacted mandibular third molar was assessed subjectively using the TMI and objectively using HR variability analysis. Our findings suggest that some patients do not have symptoms specific to dysautonomia but have an imbalance of autonomic function before extraction of the impacted mandibular third molar, and TMI can identify such patients.
自主神经系统(ANS)活动失衡引发了人们对牙科治疗期间全身并发症发展的担忧。本研究的目的是确定在下颌阻生第三磨牙拔除术前进行的一项心理测试(东邦医学指数(TMI))是否能够识别出自主神经功能可能失衡的患者。
在这项前瞻性研究中,根据TMI的结果,将34名无全身疾病史的健康成年患者分为自主神经失衡组(II型、III型、IV型)或对照组(I型)。我们评估了下颌阻生第三磨牙拔除术前的交感神经系统活动(低频/高频(LF/HF))、副交感神经活动、心率(HR)和收缩压(SBP)值。
自主神经失衡组术前的LF/HF和SBP显著高于对照组。此外,自主神经失衡组术前的HF值显著低于对照组(曼-惠特尼U检验,p<0.05);未发现两组在HR方面存在显著差异(曼-惠特尼U检验,p<0.05)。
使用TMI主观评估了下颌阻生第三磨牙拔除术前的ANS活动,并使用心率变异性分析进行了客观评估。我们的研究结果表明,一些患者没有自主神经功能障碍的特定症状,但在下颌阻生第三磨牙拔除术前存在自主神经功能失衡,且TMI能够识别出这类患者。