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多发性骨髓瘤的皮肤受累。一种罕见情况。

Cutaneous involvement in multiple myeloma. A rare entity.

作者信息

Rapparini L, Pileri A, Robuffo S, Agostinelli C, La Placa Michelangelo

机构信息

Dermatology Unit IRCCS Azienda Ospedaliero-Universitaria di Bologna Bologna Italy.

Department of Medical and Surgical Sciences Alma Mater Studiorum University of Bologna Italy.

出版信息

Clin Case Rep. 2025 Jan 24;13(2):e9476. doi: 10.1002/ccr3.9476. eCollection 2025 Feb.

DOI:10.1002/ccr3.9476
PMID:39868404
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11761395/
Abstract

Cutaneous involvement in multiple myeloma is rare and may present as nodules mimicking other lymphoid neoplasms. It typically occurs late in the course of the disease and is associated with an aggressive clinical course and poor prognosis.

摘要

多发性骨髓瘤的皮肤受累较为罕见，可能表现为类似其他淋巴瘤的结节。它通常在疾病进程的后期出现，与侵袭性临床病程及不良预后相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c221/11761395/026ebfab5043/CCR3-13-e9476-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c221/11761395/0fd68e1597d8/CCR3-13-e9476-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c221/11761395/026ebfab5043/CCR3-13-e9476-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c221/11761395/0fd68e1597d8/CCR3-13-e9476-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c221/11761395/026ebfab5043/CCR3-13-e9476-g001.jpg

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本文引用的文献

1
Cutaneous Involvement in Plasma Cell Myeloma.浆细胞骨髓瘤的皮肤累及。
Am J Clin Pathol. 2021 Jan 4;155(1):106-116. doi: 10.1093/ajcp/aqaa122.
2
International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma.国际骨髓瘤工作组更新了多发性骨髓瘤的诊断标准。
Lancet Oncol. 2014 Nov;15(12):e538-48. doi: 10.1016/S1470-2045(14)70442-5. Epub 2014 Oct 26.
3
The spectrum of cutaneous disease in multiple myeloma.
J Am Acad Dermatol. 2003 Apr;48(4):497-507. doi: 10.1067/mjd.2003.180.