小鼠肿瘤中三羧酸循环的通量测量 - Suppr

Suppr

超能文献

Flux measurements of the tricarboxylic acid cycle in the tumors of mice.

作者信息

Liu Shiyu, Locasale Jason W

机构信息

Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, United States.

出版信息

Life Metab. 2023 May 24;2(3):load020. doi: 10.1093/lifemeta/load020. eCollection 2023 Jun.

DOI:10.1093/lifemeta/load020

PMID:39872011

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11749565/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5459/11749565/441000c46c67/load020_fig1.jpg

相似文献

Flux measurements of the tricarboxylic acid cycle in the tumors of mice.

Life Metab. 2023 May 24;2(3):load020. doi: 10.1093/lifemeta/load020. eCollection 2023 Jun.

Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice.

J Biol Chem. 2006 Jul 14;281(28):19000-8. doi: 10.1074/jbc.M600050200. Epub 2006 May 2.

In vivo 13C NMR measurements of hepatocellular tricarboxylic acid cycle flux.

J Biol Chem. 1998 May 15;273(20):12187-94. doi: 10.1074/jbc.273.20.12187.

Quantification of carbon fluxes through the tricarboxylic acid cycle in early germinating lettuce embryos.

J Biol Chem. 1988 Sep 5;263(25):12278-87.

Effects of insulin and cytosolic redox state on glucose production pathways in the isolated perfused mouse liver measured by integrated 2H and 13C NMR.

Biochem J. 2006 Mar 1;394(Pt 2):465-73. doi: 10.1042/BJ20051174.

The interaction of glycolysis, gluconeogenesis and the tricarboxylic acid cycle in rat liver in vivo.

Biochem J. 1968 Nov;110(2):337-62. doi: 10.1042/bj1100337.

The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation.

Cell Rep. 2021 Jun 15;35(11):109252. doi: 10.1016/j.celrep.2021.109252.

Indexing tricarboxylic acid cycle flux in intact hearts by carbon-13 nuclear magnetic resonance.

Circ Res. 1992 Feb;70(2):392-408. doi: 10.1161/01.res.70.2.392.

Analysis of tricarboxylic acid-cycle metabolism of hepatoma cells by comparison of 14CO2 ratios.

Biochem J. 1987 Sep 15;246(3):633-9. doi: 10.1042/bj2460633.

Impaired tricarboxylic acid cycle flux and mitochondrial aerobic respiration during isoproterenol induced myocardial ischemia is rescued by bilobalide.

J Pharm Anal. 2021 Dec;11(6):764-775. doi: 10.1016/j.jpha.2020.08.008. Epub 2020 Aug 26.

本文引用的文献

Slow TCA flux and ATP production in primary solid tumours but not metastases.

Nature. 2023 Feb;614(7947):349-357. doi: 10.1038/s41586-022-05661-6. Epub 2023 Feb 1.

Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo.

Cell Metab. 2018 Nov 6;28(5):793-800.e2. doi: 10.1016/j.cmet.2018.07.020. Epub 2018 Aug 23.

Metabolomics and Isotope Tracing.

Cell. 2018 May 3;173(4):822-837. doi: 10.1016/j.cell.2018.03.055.

Understanding metabolism with flux analysis: From theory to application.

Metab Eng. 2017 Sep;43(Pt B):94-102. doi: 10.1016/j.ymben.2016.09.005. Epub 2016 Sep 22.

The Warburg Effect: How Does it Benefit Cancer Cells?

Trends Biochem Sci. 2016 Mar;41(3):211-218. doi: 10.1016/j.tibs.2015.12.001. Epub 2016 Jan 5.

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.

Nature. 2014 Oct 30;514(7524):628-32. doi: 10.1038/nature13611. Epub 2014 Aug 10.

Isotopically non-stationary metabolic flux analysis: complex yet highly informative.

Curr Opin Biotechnol. 2013 Dec;24(6):979-86. doi: 10.1016/j.copbio.2013.03.024. Epub 2013 Apr 24.

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.

Proc Natl Acad Sci U S A. 2010 May 11;107(19):8788-93. doi: 10.1073/pnas.1003428107. Epub 2010 Apr 26.

Utilization of energy-providing substrates in the isolated working rat heart.

Biochem J. 1980 Mar 15;186(3):701-11. doi: 10.1042/bj1860701.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验

Flux measurements of the tricarboxylic acid cycle in the tumors of mice.

作者信息

Liu Shiyu, Locasale Jason W

机构信息

Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, United States.

出版信息

Life Metab. 2023 May 24;2(3):load020. doi: 10.1093/lifemeta/load020. eCollection 2023 Jun.

DOI:10.1093/lifemeta/load020

PMID:39872011

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11749565/

Abstract

摘要

相似文献

Flux measurements of the tricarboxylic acid cycle in the tumors of mice.

Life Metab. 2023 May 24;2(3):load020. doi: 10.1093/lifemeta/load020. eCollection 2023 Jun.

Diminished hepatic gluconeogenesis via defects in tricarboxylic acid cycle flux in peroxisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha)-deficient mice.

J Biol Chem. 2006 Jul 14;281(28):19000-8. doi: 10.1074/jbc.M600050200. Epub 2006 May 2.

In vivo 13C NMR measurements of hepatocellular tricarboxylic acid cycle flux.

J Biol Chem. 1998 May 15;273(20):12187-94. doi: 10.1074/jbc.273.20.12187.

Quantification of carbon fluxes through the tricarboxylic acid cycle in early germinating lettuce embryos.

J Biol Chem. 1988 Sep 5;263(25):12278-87.

Effects of insulin and cytosolic redox state on glucose production pathways in the isolated perfused mouse liver measured by integrated 2H and 13C NMR.

Biochem J. 2006 Mar 1;394(Pt 2):465-73. doi: 10.1042/BJ20051174.

The interaction of glycolysis, gluconeogenesis and the tricarboxylic acid cycle in rat liver in vivo.

Biochem J. 1968 Nov;110(2):337-62. doi: 10.1042/bj1100337.

The heme synthesis-export system regulates the tricarboxylic acid cycle flux and oxidative phosphorylation.

Cell Rep. 2021 Jun 15;35(11):109252. doi: 10.1016/j.celrep.2021.109252.

Indexing tricarboxylic acid cycle flux in intact hearts by carbon-13 nuclear magnetic resonance.

Circ Res. 1992 Feb;70(2):392-408. doi: 10.1161/01.res.70.2.392.

Analysis of tricarboxylic acid-cycle metabolism of hepatoma cells by comparison of 14CO2 ratios.

Biochem J. 1987 Sep 15;246(3):633-9. doi: 10.1042/bj2460633.

Impaired tricarboxylic acid cycle flux and mitochondrial aerobic respiration during isoproterenol induced myocardial ischemia is rescued by bilobalide.

J Pharm Anal. 2021 Dec;11(6):764-775. doi: 10.1016/j.jpha.2020.08.008. Epub 2020 Aug 26.

本文引用的文献

Slow TCA flux and ATP production in primary solid tumours but not metastases.

Nature. 2023 Feb;614(7947):349-357. doi: 10.1038/s41586-022-05661-6. Epub 2023 Feb 1.

Isotope Tracing of Human Clear Cell Renal Cell Carcinomas Demonstrates Suppressed Glucose Oxidation In Vivo.

Cell Metab. 2018 Nov 6;28(5):793-800.e2. doi: 10.1016/j.cmet.2018.07.020. Epub 2018 Aug 23.

Metabolomics and Isotope Tracing.

Cell. 2018 May 3;173(4):822-837. doi: 10.1016/j.cell.2018.03.055.

Understanding metabolism with flux analysis: From theory to application.

Metab Eng. 2017 Sep;43(Pt B):94-102. doi: 10.1016/j.ymben.2016.09.005. Epub 2016 Sep 22.

The Warburg Effect: How Does it Benefit Cancer Cells?

Trends Biochem Sci. 2016 Mar;41(3):211-218. doi: 10.1016/j.tibs.2015.12.001. Epub 2016 Jan 5.

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function.

Nature. 2014 Oct 30;514(7524):628-32. doi: 10.1038/nature13611. Epub 2014 Aug 10.

Isotopically non-stationary metabolic flux analysis: complex yet highly informative.

Curr Opin Biotechnol. 2013 Dec;24(6):979-86. doi: 10.1016/j.copbio.2013.03.024. Epub 2013 Apr 24.

Mitochondrial metabolism and ROS generation are essential for Kras-mediated tumorigenicity.

Proc Natl Acad Sci U S A. 2010 May 11;107(19):8788-93. doi: 10.1073/pnas.1003428107. Epub 2010 Apr 26.

Utilization of energy-providing substrates in the isolated working rat heart.

Biochem J. 1980 Mar 15;186(3):701-11. doi: 10.1042/bj1860701.