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系统性红斑狼疮患者的浅表真菌病一例。

A Case of Superficial Mycoses in a Patient with Systemic Lupus Erythematosus.

作者信息

Li Zhen, Lu Jiejie, Yang ZhiLi

机构信息

Plastic and Cosmetic Center, The Fifth People's Hospital of Hainan Province, Haikou, Hainan, People's Republic of China.

出版信息

Clin Cosmet Investig Dermatol. 2025 Jan 23;18:245-250. doi: 10.2147/CCID.S496301. eCollection 2025.

Abstract

Superficial mycoses are characterized by the infection of keratinized tissues such as the epidermis, hair, and nails. A 52-year-old woman from Hainan Province, China is reported in this study. The patient presents with large erythematous scales on her head, face, and disfigured nails over a 2-year period. The fungal infection was further aggravated by the patient's 10-year history of SLE and long-term immunosuppressive drug therapy. Ultimately, Fungal microscopy and culture results were consistent with superficial mycosis. After 6 months of treatment with terbinafine and itraconazole, the patient's rash subsided, and fungal microscopy was negative. There was no recurrence after six months of follow-up.

摘要

浅表真菌病的特征是角质化组织如表皮、毛发和指甲受到感染。本研究报告了一名来自中国海南省的52岁女性。该患者在两年时间里头部、面部出现大片红斑鳞屑,指甲损毁。患者有10年系统性红斑狼疮病史且长期接受免疫抑制药物治疗,真菌感染进一步加重。最终,真菌显微镜检查和培养结果与浅表真菌病相符。使用特比萘芬和伊曲康唑治疗6个月后,患者皮疹消退,真菌显微镜检查呈阴性。随访6个月无复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1cf9/11771178/49620c5a1cb3/CCID-18-245-g0001.jpg

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