Seki Masayoshi, Sugiyama Mizuki, Maeda Takuya, Kasai Fumihito
Department of Rehabilitation Center, Koto Toyosu Hospital, Showa University, Tokyo, JPN.
Department of Rehabilitation Medicine, School of Medicine, Showa University, Tokyo, JPN.
Cureus. 2024 Dec 27;16(12):e76494. doi: 10.7759/cureus.76494. eCollection 2024 Dec.
Tetanus is a rare but life-threatening neurological disorder caused by neurotoxins produced by . Although mortality rates have significantly decreased with modern intensive care, severe cases remain challenging due to prolonged Intensive Care Unit (ICU) stays, complications, and rehabilitation barriers. We report the case of an 81-year-old male with a history of hypertension and femoral neck fracture who developed severe tetanus following a contaminated forehead laceration. Despite appropriate wound management, symptoms progressed rapidly, including trismus, generalized muscle spasms, opisthotonus, and respiratory failure requiring mechanical ventilation. Rehabilitation therapy began on the 10th day of hospitalization and focused on positioning techniques and passive range-of-motion exercises to reduce opisthotonus, preserve joint mobility, and prevent contractures. However, complications such as pneumonia, septic shock, and autonomic instability led to interruptions in therapy. By transfer on the 80th day, muscle tone had improved (Adductor Tone Rating: 2→1), and functional independence, measured by the Barthel Index, reached 10 points. Despite persistent spasticity in the upper limbs and finger contractures, early rehabilitation and multidisciplinary collaboration mitigated further functional decline. This case highlights the importance of initiating tailored rehabilitation early, even amidst life-saving interventions, to address the unique complexities of severe tetanus and prevent secondary complications such as disuse syndrome.
破伤风是一种由破伤风杆菌产生的神经毒素引起的罕见但危及生命的神经系统疾病。尽管随着现代重症监护技术的发展,死亡率已显著下降,但由于重症监护病房(ICU)住院时间延长、并发症以及康复障碍,严重病例仍然具有挑战性。我们报告了一例81岁男性患者,有高血压和股骨颈骨折病史,因前额裂伤感染后发生严重破伤风。尽管进行了适当的伤口处理,但症状迅速进展,包括牙关紧闭、全身肌肉痉挛、角弓反张以及需要机械通气的呼吸衰竭。康复治疗于住院第10天开始,重点是定位技术和被动关节活动度练习,以减轻角弓反张、保持关节活动度并预防挛缩。然而,诸如肺炎、感染性休克和自主神经不稳定等并发症导致治疗中断。到第80天转院时,肌张力有所改善(内收肌肌张力评分:2→1),用巴氏指数衡量的功能独立性达到10分。尽管上肢持续痉挛和手指挛缩,但早期康复和多学科协作减轻了进一步的功能衰退。该病例强调了即使在进行挽救生命的干预措施期间,尽早启动针对性康复的重要性,以应对严重破伤风的独特复杂性并预防诸如废用综合征等继发性并发症。