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7S RNA is surveilling mitochondrial DNA transcription.

作者信息

Wu Hao, Chen Ling-Ling

机构信息

State Key Laboratory of Molecular Biology, Shanghai Key Laboratory of Molecular Andrology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.

School of Life Science and Technology, ShanghaiTech University, Shanghai, China.

出版信息

Life Metab. 2022 Jun 16;1(1):8-9. doi: 10.1093/lifemeta/loac008. eCollection 2022 Aug.

DOI:10.1093/lifemeta/loac008
PMID:39872689
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11749716/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb52/11749716/39a7841719a2/loac008_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb52/11749716/39a7841719a2/loac008_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bb52/11749716/39a7841719a2/loac008_fig1.jpg

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1
7S RNA is surveilling mitochondrial DNA transcription.7S RNA正在监测线粒体DNA转录。
Life Metab. 2022 Jun 16;1(1):8-9. doi: 10.1093/lifemeta/loac008. eCollection 2022 Aug.
2
Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.非编码 7S RNA 通过线粒体 RNA 聚合酶二聚化抑制转录。
Cell. 2022 Jun 23;185(13):2309-2323.e24. doi: 10.1016/j.cell.2022.05.006. Epub 2022 Jun 2.
3
Mechanism of mammalian mitochondrial DNA replication: import of mitochondrial transcription factor A into isolated mitochondria stimulates 7S DNA synthesis.哺乳动物线粒体DNA复制机制:线粒体转录因子A导入分离的线粒体可刺激7S DNA合成。
Nucleic Acids Res. 2001 Sep 1;29(17):3657-63. doi: 10.1093/nar/29.17.3657.
4
Suppression of mitochondrial transcription initiation complexes changes the balance of replication intermediates of mitochondrial DNA and reduces 7S DNA in cultured human cells.线粒体转录起始复合物的抑制改变了线粒体DNA复制中间体的平衡,并减少了培养的人类细胞中的7S DNA。
J Biochem. 2016 Jul;160(1):49-57. doi: 10.1093/jb/mvw010. Epub 2016 Feb 8.
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RNase H1 Regulates Mitochondrial Transcription and Translation the Degradation of 7S RNA.核糖核酸酶H1调节线粒体转录和翻译以及7S RNA的降解。
Front Genet. 2020 Jan 31;10:1393. doi: 10.3389/fgene.2019.01393. eCollection 2019.
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Circulating mitochondrial long non-coding 7S RNA in primary health care patients with depression/anxiety.患有抑郁症/焦虑症的初级医疗保健患者体内的循环线粒体长链非编码7S RNA
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Mitochondrial single-stranded DNA binding protein is required for maintenance of mitochondrial DNA and 7S DNA but is not required for mitochondrial nucleoid organisation.线粒体单链DNA结合蛋白是维持线粒体DNA和7S DNA所必需的,但对于线粒体类核组织并非必需。
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Accumulation of mitochondrial 7S DNA in idiopathic and LRRK2 associated Parkinson's disease.线粒体 7S DNA 在特发性和 LRRK2 相关帕金森病中的积累。
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Transcription in vitro and in vivo of the 7S RNA gene associated with the ribosomal RNA operon in the hyperthermophilic archaeon Methanothermus fervidus.嗜热古菌嗜热栖热甲烷菌中与核糖体RNA操纵子相关的7S RNA基因的体外和体内转录。
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Transcription of human 7S K DNA in vitro and in vivo is exclusively controlled by an upstream promoter.人7S K DNA在体外和体内的转录完全由一个上游启动子控制。
Nucleic Acids Res. 1988 Feb 25;16(4):1319-31. doi: 10.1093/nar/16.4.1319.

本文引用的文献

1
Non-coding 7S RNA inhibits transcription via mitochondrial RNA polymerase dimerization.非编码 7S RNA 通过线粒体 RNA 聚合酶二聚化抑制转录。
Cell. 2022 Jun 23;185(13):2309-2323.e24. doi: 10.1016/j.cell.2022.05.006. Epub 2022 Jun 2.
2
Mitochondrial long non-coding RNA GAS5 tunes TCA metabolism in response to nutrient stress.线粒体长非编码 RNA GAS5 响应营养胁迫调节 TCA 代谢。
Nat Metab. 2021 Jan;3(1):90-106. doi: 10.1038/s42255-020-00325-z. Epub 2021 Jan 4.
3
Gene regulation by long non-coding RNAs and its biological functions.
长非编码 RNA 的基因调控及其生物学功能。
Nat Rev Mol Cell Biol. 2021 Feb;22(2):96-118. doi: 10.1038/s41580-020-00315-9. Epub 2020 Dec 22.
4
Mitochondrial Epigenetics: Non-Coding RNAs as a Novel Layer of Complexity.线粒体表观遗传学:非编码 RNA 作为复杂性的新层次。
Int J Mol Sci. 2020 Mar 6;21(5):1838. doi: 10.3390/ijms21051838.
5
Mitochondrial double-stranded RNA triggers antiviral signalling in humans.线粒体双链 RNA 触发人类抗病毒信号转导。
Nature. 2018 Aug;560(7717):238-242. doi: 10.1038/s41586-018-0363-0. Epub 2018 Jul 25.
6
Structural Basis of Mitochondrial Transcription Initiation.线粒体转录起始的结构基础
Cell. 2017 Nov 16;171(5):1072-1081.e10. doi: 10.1016/j.cell.2017.10.036.
7
ALUternative Regulation for Gene Expression.基因表达的 ALU 替代调控。
Trends Cell Biol. 2017 Jul;27(7):480-490. doi: 10.1016/j.tcb.2017.01.002. Epub 2017 Feb 10.
8
Mitochondrial diseases.线粒体疾病。
Nat Rev Dis Primers. 2016 Oct 20;2:16080. doi: 10.1038/nrdp.2016.80.
9
Helicase SUV3, polynucleotide phosphorylase, and mitochondrial polyadenylation polymerase form a transient complex to modulate mitochondrial mRNA polyadenylated tail lengths in response to energetic changes.解旋酶SUV3、多核苷酸磷酸化酶和线粒体多聚腺苷酸化聚合酶形成一个瞬时复合物,以响应能量变化来调节线粒体mRNA的多聚腺苷酸化尾长度。
J Biol Chem. 2014 Jun 13;289(24):16727-35. doi: 10.1074/jbc.M113.536540. Epub 2014 Apr 25.
10
B2 RNA and Alu RNA repress transcription by disrupting contacts between RNA polymerase II and promoter DNA within assembled complexes.B2 RNA和Alu RNA通过破坏组装复合物中RNA聚合酶II与启动子DNA之间的接触来抑制转录。
Proc Natl Acad Sci U S A. 2009 Apr 7;106(14):5569-74. doi: 10.1073/pnas.0810738106. Epub 2009 Mar 23.