Sciarrone Salvatore Stefano, Fini Lucia, De Luca Luca
Department of Surgery, Gastroenterology and Digestive Endoscopy Unit, ASST Santi Paolo e Carlo, University of Milan, Milan 20142, Lombardy, Italy.
World J Gastrointest Surg. 2025 Jan 27;17(1):100554. doi: 10.4240/wjgs.v17.i1.100554.
Trans-jugular intrahepatic portosystemic stent shunting (TIPSS) has been in use for many years with great results and many evolutions. The procedure essentially involves the insertion of a metal covert stent to create an Hepato-Hepatic portosystemic shunt. Over time, TIPSS has become the subject of many studies aimed at examining its clinical utility and evaluating the results of using TIPSS to manage complications related to portal hypertension. From the outset, this procedure has been met with hope and enthusiasm and give the chance to consider another possibility to treat the complications of portal hypertension without the use of surgery. Considering that TIPSS is an attractive alternative to shunt surgery because it does not require the use of general anesthesia or laparotomy, in fact this method is applicable to many patients with severe liver disease not suitable for it. TIPSS has been studied for the management of variceal bleeding, ascites, hepatic hydrothorax, hepatorenal syndrome, and other types of cirrhosis. However, some drawbacks of the TIPSS, such as shunt stenosis and hepatic encephalopathy, have also been reported in the literature. On the basis of the available evidence and the new epidemiological findings regarding liver disease, the following question may be posed: What is the place of TIPSS in current clinical practice?
经颈静脉肝内门体静脉支架分流术(TIPSS)已应用多年,效果显著且有诸多进展。该手术主要是插入一个金属覆膜支架以建立肝内门体分流。随着时间推移,TIPSS已成为众多研究的主题,这些研究旨在检验其临床效用,并评估使用TIPSS治疗门静脉高压相关并发症的结果。从一开始,该手术就带来了希望和热情,为不通过手术治疗门静脉高压并发症提供了另一种可能。鉴于TIPSS是分流手术的一种有吸引力的替代方法,因为它不需要全身麻醉或开腹手术,实际上这种方法适用于许多不适合进行分流手术的严重肝病患者。TIPSS已被用于研究治疗静脉曲张出血、腹水、肝性胸水、肝肾综合征及其他类型的肝硬化。然而,文献中也报道了TIPSS的一些缺点,如分流狭窄和肝性脑病。基于现有证据以及关于肝病的新流行病学发现,可能会提出以下问题:TIPSS在当前临床实践中的地位如何?