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CD157 selectively identifies hPSCs with enhanced hepatic differentiation capacity.

作者信息

Li Shuang, Jiang Dacheng, Li Xin, Zhao Yongxu, Gu Xiaosong, Jiang Chunping, Ding Qiurong

机构信息

CAS Key Laboratory of Nutrition, Metabolism and Food Safety, Shanghai Institute of Nutrition and Health, Shanghai Institutes for Biological Sciences, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

Center for Metabolic Disease Drug Research, Shandong Laboratory of Yantai Drug Discovery, Bohai Rim Advanced Research Institute for Drug Discovery, Yantai 264117, China.

出版信息

Life Med. 2024 Jun 5;3(4):lnae026. doi: 10.1093/lifemedi/lnae026. eCollection 2024 Aug.

DOI:10.1093/lifemedi/lnae026
PMID:39872867
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11749559/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f18/11749559/2cd826e466de/lnae026_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f18/11749559/2cd826e466de/lnae026_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f18/11749559/2cd826e466de/lnae026_fig1.jpg

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1
CD157 selectively identifies hPSCs with enhanced hepatic differentiation capacity.CD157可选择性地识别具有增强肝分化能力的人多能干细胞。
Life Med. 2024 Jun 5;3(4):lnae026. doi: 10.1093/lifemedi/lnae026. eCollection 2024 Aug.
2
Modulation of CD157 expression in multi-lineage myeloid differentiation of promyelocytic cell lines.早幼粒细胞系多谱系髓系分化过程中CD157表达的调控
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3
An immature rat lymphocyte marker CD157: striking differences in the expression between mice and rats.一种未成熟大鼠淋巴细胞标志物CD157:小鼠与大鼠之间表达的显著差异。
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Overexpression of CD157 contributes to epithelial ovarian cancer progression by promoting mesenchymal differentiation.CD157 的过表达通过促进间充质分化促进卵巢上皮性癌的进展。
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CD157 enhances malignant pleural mesothelioma aggressiveness and predicts poor clinical outcome.CD157增强恶性胸膜间皮瘤的侵袭性并预示不良临床结局。
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CD157: From immunoregulatory protein to potential therapeutic target.CD157:从免疫调节蛋白到潜在的治疗靶点。
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CD38, CD157, and RAGE as Molecular Determinants for Social Behavior.CD38、CD157 和 RAGE 作为社会行为的分子决定因素。
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Binding of CD157 protein to fibronectin regulates cell adhesion and spreading.CD157 蛋白与纤连蛋白的结合调节细胞黏附和铺展。
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Expression Profile of CD157 Reveals Functional Heterogeneity of Capillaries in Human Dermal Skin.CD157的表达谱揭示了人类真皮皮肤中毛细血管的功能异质性。
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CD157: From Myeloid Cell Differentiation Marker to Therapeutic Target in Acute Myeloid Leukemia.CD157:从髓系细胞分化标志物到急性髓系白血病的治疗靶点。
Cells. 2019 Dec 5;8(12):1580. doi: 10.3390/cells8121580.

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RIG-I-driven CDKN1A stabilization reinforces cellular senescence.视黄酸诱导基因I(RIG-I)驱动的细胞周期蛋白依赖性激酶抑制剂1A(CDKN1A)稳定增强细胞衰老。
Sci China Life Sci. 2025 Mar 24. doi: 10.1007/s11427-024-2844-8.

本文引用的文献

1
Single cell heterogeneity in human pluripotent stem cells.人类多能干细胞中的单细胞异质性。
BMB Rep. 2021 Oct;54(10):505-515. doi: 10.5483/BMBRep.2021.54.10.094.
2
NAD metabolism: pathophysiologic mechanisms and therapeutic potential.NAD 代谢:病理生理机制与治疗潜力。
Signal Transduct Target Ther. 2020 Oct 7;5(1):227. doi: 10.1038/s41392-020-00311-7.
3
Cellular metabolism and homeostasis in pluripotency regulation.细胞代谢与多能性调控中的细胞内稳态
Protein Cell. 2020 Sep;11(9):630-640. doi: 10.1007/s13238-020-00755-1. Epub 2020 Jul 8.
4
CD157 Marks Tissue-Resident Endothelial Stem Cells with Homeostatic and Regenerative Properties.CD157 标记具有稳态和再生特性的组织驻留内皮干细胞。
Cell Stem Cell. 2018 Mar 1;22(3):384-397.e6. doi: 10.1016/j.stem.2018.01.010. Epub 2018 Feb 8.
5
Metabolism in Pluripotent Stem Cells and Early Mammalian Development.多能干细胞和早期哺乳动物发育中的代谢。
Cell Metab. 2018 Feb 6;27(2):332-338. doi: 10.1016/j.cmet.2018.01.008.
6
Proteomics. Tissue-based map of the human proteome.蛋白质组学。人类蛋白质组组织图谱。
Science. 2015 Jan 23;347(6220):1260419. doi: 10.1126/science.1260419.
7
Origins and implications of pluripotent stem cell variability and heterogeneity.多能干细胞变异性和异质性的起源和意义。
Nat Rev Mol Cell Biol. 2013 Jun;14(6):357-68. doi: 10.1038/nrm3584. Epub 2013 May 15.
8
CD157, the Janus of CD38 but with a unique personality.CD157,CD38的两面神,但具有独特个性。
Cell Biochem Funct. 2002 Dec;20(4):309-22. doi: 10.1002/cbf.978.
9
The family of toxin-related ecto-ADP-ribosyltransferases in humans and the mouse.人类和小鼠中与毒素相关的胞外ADP核糖基转移酶家族。
Protein Sci. 2002 Jul;11(7):1657-70. doi: 10.1110/ps.0200602.