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[肥胖对德国初次髋膝关节置换术后中期结局的影响:来自EPRD的分析]

[Influence of obesity on midterm outcome after primary hip and knee arthroplasty in Germany : Analysis from the EPRD].

作者信息

Lützner Jörg, Melsheimer Oliver, Grimberg Alexander, Perka Carsten, Günther Klaus-Peter, Lützner Cornelia, Steinbrück Arnd

机构信息

UniversitätsCentrum für Orthopädie, Unfall- und Plastische Chirurgie (OUPC), Universitätsklinikum Carl Gustav Carus, TU Dresden, Fetscherstr. 74, 01307, Dresden, Deutschland.

Endoprothesenregister Deutschland (EPRD), Berlin, Deutschland.

出版信息

Orthopadie (Heidelb). 2025 Apr;54(4):244-252. doi: 10.1007/s00132-025-04614-x. Epub 2025 Jan 28.

Abstract

OBJECTIVES

To determine the influence of obesity on revision rates and mortality after primary elective hip and knee arthroplasty in Germany.

MATERIALS AND METHODS

In the German Arthroplasty Registry (EPRD) there were 403,073 elective total hip arthroplasties (THA), 320,913 bicondylar total knee arthroplasties (TKA) and 48,480 unicondylar knee arthroplasties (UKA) with valid BMI available for analysis. Cumulative revision rates and 1‑year mortality was calculated for BMI groups.

RESULTS

There were increased revision rates with increasing BMI, most distinctive for septic revisions in THA during the first year after surgery (non-obese 0.7%, obesity grade 1 1.3%, grade 2 2.1%, grade 3 4.2%). In TKA and UKA this increase was generally less pronounced. Age- and gender-standardized mortality was lower than expected in most groups, but also increasing with increasing BMI.

CONCLUSION

The risk for revisions in obese patients is more distinctive in hip arthroplasty than in knee arthroplasty and is especially high in morbidly obese patients (BMI ≥ 40 kg/m). Nonetheless, this risk may be acceptable for affected patients. Therefore, the possible benefits and risks of an arthroplasty should be weighed against each other and individually discussed with the patient.

摘要

目的

确定肥胖对德国初次择期髋关节和膝关节置换术后翻修率及死亡率的影响。

材料与方法

在德国关节置换登记处(EPRD),有403,073例择期全髋关节置换术(THA)、320,913例双髁全膝关节置换术(TKA)和48,480例单髁膝关节置换术(UKA),其有效BMI可用于分析。计算各BMI组的累积翻修率和1年死亡率。

结果

随着BMI的增加,翻修率升高,在THA术后第一年的感染性翻修中最为明显(非肥胖者0.7%,肥胖1级1.3%,2级2.1%,3级4.2%)。在TKA和UKA中,这种增加通常不太明显。大多数组的年龄和性别标准化死亡率低于预期,但也随着BMI的增加而升高。

结论

肥胖患者髋关节置换术的翻修风险比膝关节置换术更显著,在病态肥胖患者(BMI≥40 kg/m²)中尤其高。尽管如此,对于受影响的患者来说,这种风险可能是可以接受的。因此,关节置换术可能的益处和风险应该相互权衡,并与患者进行单独讨论。

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