Wu Zhenni, Xie Mingxing, Zhang Li, He Qing, Gao Lang, Ji Mengmeng, Lin Yixia, Li Yuman
Department of Ultrasound Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Clinical Research Center for Medical Imaging in Hubei Province, Wuhan, China.
Front Cardiovasc Med. 2025 Jan 14;11:1504063. doi: 10.3389/fcvm.2024.1504063. eCollection 2024.
Valvular heart disease (VHD) leading to inadequate hemodynamic circulation is a major cause of cardiovascular morbidity and mortality worldwide. Right ventricular-pulmonary artery (RV-PA) coupling integrates the ability of RV contractility to adapt to increased pulmonary arterial afterload. If the right ventricle cannot adapt to the elevated afterload by increasing its contractile function, RV-PA uncoupling occurs. RV-PA uncoupling has been shown to be associated with poor outcomes in VHD. This review summarizes the prognostic significance of RV-PA coupling in patients with VHD.
导致血流动力学循环不足的心脏瓣膜病（VHD）是全球心血管疾病发病率和死亡率的主要原因。右心室-肺动脉（RV-PA）耦合整合了右心室收缩力适应肺动脉后负荷增加的能力。如果右心室不能通过增加其收缩功能来适应升高的后负荷，就会发生RV-PA解耦联。RV-PA解耦联已被证明与VHD患者的不良预后相关。本综述总结了RV-PA耦合在VHD患者中的预后意义。
