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新冠病毒感染后的情绪障碍:单中心经验

Mood disorders after COVID-19 infection: a single-center experience.

作者信息

Uzer Fatih, Cilli Aykut, Oner Sukriye, Emek Mestan, Yalcın Ata Nevzat

机构信息

Department of Respiratory Medicine, Akdeniz University School of Medicine, Antalya, Turkey.

Department of Public Health, Akdeniz University School of Medicine, Antalya, Turkey.

出版信息

Malawi Med J. 2025 Jan 13;36(4):238-243. doi: 10.4314/mmj.v36i4.1. eCollection 2025 Jan.

Abstract

OBJECTIVES

The present study aimed to examine mood disorders in patients discharged from the hospital due to Coronavirus Disease-19 (COVID-19).

METHODS

The study included patients who were admitted to Akdeniz University with the diagnosis of COVID-19. Post-Traumatic Stress Disorder (PTSD) Checklist - Civilian Version (PCL-5), and Beck Anxiety and Depression Inventories were administered to the patients at least 30 days after discharge.

RESULTS

A total of 215 patients were included. The median age was 56 years, and 60.9%(131) were male. There was no statistically significant difference in mood disorders scale scores between male and female. However, there was a weak negative correlation between age and PCL-5 scores (rho: -0.157, p: 0.021). The depression scores (p < 0.001), anxiety scores (p < 0.001) and PCL-5 (p = 0.001) scores were statistically significantly higher in patients with respiratory symptoms at the time of enrollment (after a mean duration of 87.9 days following discharge). Married individuals had statistically significantly lower anxiety, depression, and PCL-5 scores. Beck anxiety scores were statistically significantly higher in patients receiving systemic steroid.

CONCLUSION

A substantial portion of patients with COVID-19 suffer from mood disorders after hospital discharge. Those patients with residual symptoms who live alone and receive corticosteroid represent a vulnerable population.

摘要

目的

本研究旨在调查因冠状病毒病19(COVID-19)出院患者的情绪障碍情况。

方法

该研究纳入了因COVID-19诊断入住阿克德尼兹大学的患者。在出院至少30天后,对患者进行创伤后应激障碍检查表-平民版(PCL-5)以及贝克焦虑和抑郁量表评估。

结果

共纳入215例患者。中位年龄为56岁,男性占60.9%(131例)。男性和女性在情绪障碍量表得分上无统计学显著差异。然而,年龄与PCL-5得分之间存在微弱的负相关(rho:-0.157,p:0.021)。入组时出现呼吸道症状的患者(出院后平均87.9天),其抑郁得分(p<0.001)、焦虑得分(p<0.001)和PCL-5得分(p=0.001)在统计学上显著更高。已婚个体的焦虑、抑郁和PCL-5得分在统计学上显著更低。接受全身性类固醇治疗的患者贝克焦虑得分在统计学上显著更高。

结论

相当一部分COVID-19患者出院后患有情绪障碍。那些有残留症状、独居且接受皮质类固醇治疗的患者是弱势群体。

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Mood disorders after COVID-19 infection: a single-center experience.新冠病毒感染后的情绪障碍:单中心经验
Malawi Med J. 2025 Jan 13;36(4):238-243. doi: 10.4314/mmj.v36i4.1. eCollection 2025 Jan.

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