Cain Tara, Brinsley Jacinta, Bennett Hunter, Nelson Max, Maher Carol, Singh Ben
Alliance for Research in Exercise Nutrition and Activity (ARENA), Allied Health and Human Performance, University of South Australia, Adelaide, Australia.
PLoS One. 2025 Jan 29;20(1):e0317615. doi: 10.1371/journal.pone.0317615. eCollection 2025.
Cold-water immersion (CWI) has gained popularity as a health and wellbeing intervention among the general population.
This systematic review and meta-analysis aimed to evaluate the psychological, cognitive, and physiological effects of CWI in healthy adults.
Electronic databases were searched for randomized trials involving healthy adults aged ≥ 18 years undergoing acute or long-term CWI exposure via cold shower, ice bath, or plunge with water temperature ≤15°C for at least 30 seconds. Outcomes of interest were sleep, stress, fatigue, energy, skin health, immunity, inflammation, mental wellbeing, depression, anxiety, mood, concentration, and alertness or focus. Meta-analyses were conducted using RevMan software (version 5.4), applying random effects models to calculate standardized mean differences (SMD) between pre- and post-CWI exposure outcomes. Risk of bias was assessed using the PEDro scale.
Eleven studies were included, comprising 3177 total participants and a mean PEDro score of 6.4 (n = 7 moderate quality, n = 4 high quality). CWI interventions were performed in baths (n = 10) or showers (n = 1) at temperatures ranging from 7°C to 15°C and durations ranging from 30 seconds to 2 hours. The meta-analysis revealed significant increases in inflammation immediately (SMD: 1.03, [95% CI: 0.37, 1.68], p < 0.01) and 1 hour post CWI (SMD: 1.26, [95% CI: 0.59, 1.94], p < 0.01), indicating an acute inflammatory response. A significant reduction in stress was observed 12 hours post-CWI (SMD: -1.00, [95% CI: -1.40, -0.61], p < 0.01), however, no significant effects on stress were detected immediately (SMD: -0.09 [95% CI: -0.45, 0.63], p > 0.05), 1 hour (SMD: -0.29 [95% CI: -0.66, 0.08], p > 0.05), 24 hours (SMD: -0.06 [95% CI: -0.50, 0.38], p > 0.05), or 48 hours (SMD: 0.09 [95% CI: -0.28, 0.46], p > 0.05) post-exposure. While meta-analysis showed no significant effects on immune function immediately (SMD: -0.16 [95% CI: -0.82, 0.51], p > 0.05) or 1 hour (SMD: -0.18 [95% CI: -1.09, 0.74], p > 0.05) post-CWI, narrative synthesis suggested longer-term benefits, including a 29% reduction in sickness absence among participants who took cold showers. Improvements were also observed in sleep quality and quality of life, but not mood.
This systematic review suggests that CWI delivers time-dependent effects on inflammation, stress, immunity, sleep quality, and quality of life, offering potential practical applications for health practitioners considering CWI for stress management and wellbeing support. However, the current evidence base is constrained by few RCTs, small sample sizes, and a lack of diversity in study populations. Future high-quality RCTs are needed to examine the long-term effects of CWI, its impact on diverse health outcomes, and optimal CWI protocols. PROSPERO (ID: CRD42024500591).
冷水浸泡(CWI)作为一种健康和福祉干预措施,在普通人群中越来越受欢迎。
本系统评价和荟萃分析旨在评估CWI对健康成年人心理、认知和生理的影响。
检索电子数据库,查找涉及年龄≥18岁健康成年人的随机试验,这些成年人通过冷水淋浴、冰浴或水温≤15°C的冷水浸泡至少30秒,经历急性或长期CWI暴露。感兴趣的结果包括睡眠、压力、疲劳、精力、皮肤健康、免疫力、炎症、心理健康、抑郁、焦虑、情绪、注意力和警觉性或专注力。使用RevMan软件(5.4版)进行荟萃分析,应用随机效应模型计算CWI暴露前后结果之间的标准化平均差异(SMD)。使用PEDro量表评估偏倚风险。
纳入11项研究,共3177名参与者,平均PEDro评分为6.4(n = 7为中等质量,n = 4为高质量)。CWI干预在温度为7°C至15°C、持续时间为30秒至2小时的浴盆(n = 10)或淋浴(n = 1)中进行。荟萃分析显示,CWI后立即(SMD:1.03,[95%CI:0.37,1.68],p < 0.01)和1小时(SMD:1.26,[95%CI:0.59,1.94],p < 0.01)炎症显著增加,表明存在急性炎症反应。CWI后12小时观察到压力显著降低(SMD:-1.00,[95%CI:-1.40,-0.61],p < 0.01),然而,暴露后立即(SMD:-0.09 [95%CI:-0.45,0.63],p > 0.05)、1小时(SMD:-0.29 [95%CI:-0.66,0.08],p > 0.05)、24小时(SMD:-0.06 [95%CI:-0.50,0.38],p > 0.05)或48小时(SMD:0.09 [95%CI:-0.28,0.46],p > 0.05)未检测到对压力的显著影响。虽然荟萃分析显示CWI后立即(SMD:-0.16 [95%CI:-0.82,0.51],p > 0.05)或1小时(SMD:-0.18 [95%CI:-1.09,0.74],p > 0.05)对免疫功能无显著影响,但叙述性综合分析表明存在长期益处,包括洗冷水澡的参与者病假减少29%。睡眠质量和生活质量也有改善,但情绪没有改善。
本系统评价表明,CWI对炎症、压力、免疫力、睡眠质量和生活质量具有时间依赖性影响,为考虑将CWI用于压力管理和健康支持的健康从业者提供了潜在的实际应用。然而,目前的证据基础受到随机对照试验数量少、样本量小以及研究人群缺乏多样性的限制。需要未来进行高质量的随机对照试验,以研究CWI的长期影响、其对多种健康结果的影响以及最佳CWI方案。国际前瞻性系统评价注册库(ID:CRD42024500591)。