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盲标记亚波长超声成像

Blind-label subwavelength ultrasound imaging.

作者信息

Lin Jinuan, Ma Chu

机构信息

Department of Electrical and Computer Engineering, University of Wisconsin-Madison, 3436 Engineering Hall, 1415 Engineering Drive, Madison, WI 53706, USA.

出版信息

Sci Adv. 2025 Jan 31;11(5):eado2826. doi: 10.1126/sciadv.ado2826. Epub 2025 Jan 29.

Abstract

There is a long-existing trade-off between the imaging resolution and penetration depth in acoustic imaging caused by the diffraction limit. Most existing approaches addressing this trade-off require controlled "labels," i.e., metamaterials or contrast agents, to be deposited close to the objects and to either remain static or be tracked precisely during imaging. We propose a "blind-label" approach for acoustic subwavelength imaging. The blind labels are randomly distributed acoustic scatterers with deep-subwavelength sizes whose exact locations and trajectories are not necessary information in image reconstruction. The proposed method achieves the resolution of 0.24 wavelengths in ultrasound imaging experiments and 0.2 wavelengths in simulations, providing over 10 times improvement compared to the diffraction limit. We also elucidate the influence of scatterer size and concentration on imaging performance. The proposed "blind-label" approach relaxes the restrictions of existing acoustic subwavelength imaging technologies relying on controlled labels, therefore substantially improving the practicality of acoustic subwavelength imaging in biomedical ultrasound imaging, sonar, and nondestructive testing.

摘要

由于衍射极限,在声学成像中,成像分辨率和穿透深度之间长期存在权衡。大多数解决这种权衡的现有方法都需要将受控“标签”,即超材料或造影剂,沉积在靠近物体的位置,并在成像过程中保持静止或精确跟踪。我们提出了一种用于声学亚波长成像的“盲标签”方法。盲标签是具有深亚波长尺寸的随机分布的声学散射体,其确切位置和轨迹在图像重建中并非必要信息。所提出的方法在超声成像实验中实现了0.24波长的分辨率,在模拟中实现了0.2波长的分辨率,与衍射极限相比提高了10倍以上。我们还阐明了散射体尺寸和浓度对成像性能的影响。所提出的“盲标签”方法放宽了现有依赖受控标签的声学亚波长成像技术的限制,从而大大提高了声学亚波长成像在生物医学超声成像、声纳和无损检测中的实用性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ffba/11777185/7cf596d07bbf/sciadv.ado2826-f1.jpg

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