Cramer Iris, van Esch Rik, Verstappen Cindy, Kloeze Carla, van Bussel Bas, Stuijk Sander, Bergmans Jan, van 't Veer Marcel, Zinger Svitlana, Montenij Leon, Bouwman R Arthur, Dekker Lukas
Department of Electrical Engineering, Eindhoven University of Technology, Groene Loper 3, 5612 AZ, Eindhoven, the Netherlands.
Department of Anesthesiology, Intensive Care and Pain Medicine, Catharina Hospital, Eindhoven, the Netherlands.
J Clin Monit Comput. 2025 Jan 29. doi: 10.1007/s10877-025-01263-5.
Unobtrusive pulse rate monitoring by continuous video recording, based on remote photoplethysmography (rPPG), might enable early detection of perioperative arrhythmias in general ward patients. However, the accuracy of an rPPG-based machine learning model to monitor the pulse rate during sinus rhythm and arrhythmias is unknown. We conducted a prospective, observational diagnostic study in a cohort with a high prevalence of arrhythmias (patients undergoing elective electrical cardioversion). Pulse rate was assessed with rPPG via a visible light camera and ECG as reference, before and after cardioversion. A cardiologist categorized ECGs into normal sinus rhythm or arrhythmias requiring further investigation. A supervised machine learning model (support vector machine with Gaussian kernel) was trained using rPPG signal features from 60-s intervals and validated via leave-one-subject-out. Pulse rate measurement performance was evaluated with Bland-Altman analysis. Of 72 patients screened, 51 patients were included in the analyses, including 444 60-s intervals with normal sinus rhythm and 1130 60-s intervals of clinically relevant arrhythmias. The model showed robust discrimination (AUC 0.95 [0.93-0.96]) and good calibration. For pulse rate measurement, the bias and limits of agreement for sinus rhythm were 1.21 [- 8.60 to 11.02], while for arrhythmia, they were - 7.45 [- 35.75 to 20.86]. The machine learning model accurately identified sinus rhythm and arrhythmias using rPPG in real-world conditions. Heart rate underestimation during arrhythmias highlights the need for optimization.
基于远程光电容积脉搏波描记法(rPPG)的连续视频记录进行的无创脉搏率监测,可能有助于早期发现普通病房患者围手术期心律失常。然而,基于rPPG的机器学习模型在窦性心律和心律失常期间监测脉搏率的准确性尚不清楚。我们在心律失常患病率较高的队列(接受择期心脏电复律的患者)中进行了一项前瞻性观察性诊断研究。在心脏电复律前后,通过可见光摄像头和心电图作为参考,使用rPPG评估脉搏率。心脏病专家将心电图分类为正常窦性心律或需要进一步检查的心律失常。使用来自60秒间隔的rPPG信号特征训练一个监督机器学习模型(具有高斯核的支持向量机),并通过留一法进行验证。使用Bland-Altman分析评估脉搏率测量性能。在筛选的72例患者中,51例患者纳入分析,包括444个60秒间隔的正常窦性心律和1130个60秒间隔的临床相关心律失常。该模型显示出强大的辨别力(AUC 0.95[0.93 - 0.96])和良好的校准。对于脉搏率测量,窦性心律的偏差和一致性界限为1.21[-8.60至11.02],而对于心律失常,偏差和一致性界限为-7.45[-35.75至20.86]。该机器学习模型在实际情况下使用rPPG准确识别窦性心律和心律失常。心律失常期间心率低估突出了优化的必要性。