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2022年埃塞俄比亚西北部贡德尔大学综合专科医院成年择期手术患者术后头痛的发生率及相关因素:一项前瞻性随访研究

Incidence and factors associated with postoperative headache among adult elective surgical patients at the university of gondar comprehensive specialized hospital, northwest Ethiopia, 2022: a prospective follow-up study.

作者信息

Zegeye Sitotaw Tesfa, Aytolign Habtu Adane, Mekonnen Zemenay Ayinie, Ahmed Seid Adem

机构信息

Department of Anesthesia, School of Medicine, College of Medicine and Health sciences, Bahirdar University, Bahirdar, Ethiopia.

Department of Anesthesia, School of Medicine, College of Medicine and Health sciences, University of Gondar, Gondar, Ethiopia.

出版信息

BMC Anesthesiol. 2025 Jan 29;25(1):44. doi: 10.1186/s12871-025-02910-9.

Abstract

BACKGROUND

Postoperative headache is a medical condition that has a strong association with future recurrence and chronic headache, higher morbidity and mortality, extended hospital stays, poor quality of life and high financial burden. Despite, having these consequences, there are limited studies in the study area.

OBJECTIVE

This study aimed to assess the incidence and associated factors of postoperative headache among adult elective surgical patients at the University of Gondar Comprehensive Specialized Hospital Northwest Ethiopia, April 9 to 20 June 2022.

METHODS

An institution -based follow- up study was conducted from April 9 to June 20, 2022, at the University of Gondar Comprehensive Specialized Hospital, after ethical approval and 424 patients were included. Postoperative headache was assessed with patient interview and the response was dichotomized as present or absent. Data was collected through chart review and patient interviews using a questionnaire. Data was entered into Epidata 4.6.0 and statistical analysis was performed using stata version 14.01. Descriptive statistics was conducted to summarize patient information and determine the outcome's incidence. Binary logistic regression was conducted to identify factors associated with postoperative headache. Variables with P-value < 0.05 were considered statistically significant.

RESULTS

The overall incidence of postoperative headache in the first three postoperative days was 54.3% (228) and the response rate was 99%. Previous history of headache (AOR = 4.83, CI = 2.42 9.73), prolonged fasting (AOR = 2.28, CI = 1.44-3.60), general anesthesia (AOR = 1.96, CI = 1.25-3.07), intraoperative hypotension (AOR = 1.74,CI = 1.06-2.88), being female (AOR = 1.62,CI = 1.06-2.54) and caffeine consumption(AOR = 1.60,CI = 1.02-2.52) were significant factors associated with postoperative headache and most of patients 89(21.2%) had moderate headache.

CONCLUSION AND RECOMMENDATIONS

More than half of patients were suffered from postoperative headache. Use of general anesthesia, having prior history of headache, being female, intraoperative hypotension, caffeine consumption and prolonged preoperative fasting were strongly associated with postoperative headache. The problem needs regular assessment and treatment.

摘要

背景

术后头痛是一种与未来复发和慢性头痛、更高的发病率和死亡率、延长住院时间、生活质量差以及高经济负担密切相关的病症。尽管有这些后果,但该研究领域的研究有限。

目的

本研究旨在评估2022年4月9日至6月20日在埃塞俄比亚西北部贡德尔大学综合专科医院接受择期手术的成年患者术后头痛的发生率及相关因素。

方法

2022年4月9日至6月20日,在贡德尔大学综合专科医院进行了一项基于机构的随访研究,研究经过伦理批准,纳入了424例患者。通过患者访谈评估术后头痛情况,并将回答分为有或无。通过病历审查和使用问卷进行患者访谈收集数据。数据录入Epidata 4.6.0,并使用Stata 14.01版本进行统计分析。进行描述性统计以总结患者信息并确定结果的发生率。进行二元逻辑回归以确定与术后头痛相关的因素。P值<0.05的变量被认为具有统计学意义。

结果

术后前三天术后头痛的总体发生率为54.3%(228例),应答率为99%。既往头痛史(调整后比值比[AOR]=4.83,可信区间[CI]=2.42-9.73)、禁食时间延长(AOR=2.28,CI=1.44-3.60)、全身麻醉(AOR=1.96,CI=1.25-3.07)、术中低血压(AOR=1.74,CI=1.06-2.88)、女性(AOR=1.62,CI=1.06-2.54)和咖啡因摄入(AOR=1.60,CI=1.02-2.52)是与术后头痛相关的显著因素,大多数患者89例(21.2%)有中度头痛。

结论与建议

超过一半的患者遭受术后头痛。全身麻醉的使用、既往头痛史、女性、术中低血压、咖啡因摄入和术前禁食时间延长与术后头痛密切相关。这个问题需要定期评估和治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ba9/11776306/66ce28ea31de/12871_2025_2910_Fig1_HTML.jpg

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