2024年9月，意大利马尔凯大区佩萨罗－乌尔比诺省法诺市本土登革热疫情

Outbreak of autochthonous dengue in Fano, Pesaro-Urbino Province - Marche region, Italy, September 2024.

作者信息

Santilli Luca, Canovari Benedetta, Balducci Maria, Corbelli Giovanni, Maracci Monia, Polenta Antonio, Farinaccio Ylenia, Ginevri Francesco, Anzalone Norma, Franca Lucia, Sterza Lucia, Barchiesi Francesco

机构信息

Unit of Infection Diseases, San Salvatore Hospital, AST Pesaro Urbino, Pesaro, Italy.

Department of Biomedical Sciences and Public Health, UNIVPM, Ancona, Italy.

出版信息

Infection. 2025 Jan 30. doi: 10.1007/s15010-025-02476-1.

DOI:10.1007/s15010-025-02476-1

PMID:39883264

Abstract

Dengue is the most common arboviral disease globally. It is caused by four distinct but closely related Dengue viruses (DENV-1, -2, -3, and - 4) transmitted through bites of infected Aedes species mosquito vectors. In the last 50 years, incidence has increased 30-fold with increasing geographic expansion to new countries. Here we report the most important autochthonous Dengue epidemic in Italy ever recorded with a total of 86 confirmed cases occurring in September 2024 in Fano. They were caused by DENV-2. They were 61 Dengue fever, 21 Dengue with warning signs and no cases of severe Dengue. Our data underline the importance of considering Dengue not only as imported disease and rapidly testing all those patients with suggestive clinical pictures even if they have no travel history.

摘要

登革热是全球最常见的虫媒病毒病。它由四种不同但密切相关的登革病毒（DENV-1、-2、-3和-4）引起，这些病毒通过受感染的伊蚊属蚊媒叮咬传播。在过去50年里，随着地理范围向新国家的不断扩大，发病率增加了30倍。在此，我们报告了意大利有史以来最重要的本土登革热疫情，2024年9月在法诺共出现86例确诊病例。这些病例由DENV-2引起。其中有61例登革热、21例有警示症状的登革热，无重症登革热病例。我们的数据强调，不仅要将登革热视为输入性疾病，而且要对所有有疑似临床表现的患者迅速进行检测，即使他们没有旅行史，这一点很重要。