Fisher G B, Greer K E, Cooper P H
Int J Dermatol. 1985 Mar;24(2):101-7. doi: 10.1111/j.1365-4362.1985.tb05389.x.
Two patients with eosinophilic cellulitis are reported and 22 additional cases from the literature are reviewed. Cutaneous lesions are variable in appearance and may be confused with cellulitis, urticaria, insect bites, or contact dermatitis. Microscopically, there is a dense dermal infiltrate of eosinophils. Subsequently, granulomatous features with characteristic "flame figures" become apparent. Peripheral eosinophilia is common. The etiology of eosinophilic cellulitis is unknown, although a hypersensitivity mechanism is suspected. Treatment with systemic corticosteroids is frequently effective, but the disease is often characterized by relapses that can occur for several years.
报告了2例嗜酸性粒细胞性蜂窝织炎患者，并回顾了文献中的另外22例病例。皮肤病变外观各异，可能与蜂窝织炎、荨麻疹、昆虫叮咬或接触性皮炎相混淆。显微镜下，真皮有密集的嗜酸性粒细胞浸润。随后，出现具有特征性“火焰状图形”的肉芽肿特征。外周血嗜酸性粒细胞增多很常见。尽管怀疑有超敏反应机制，但嗜酸性粒细胞性蜂窝织炎的病因尚不清楚。全身用皮质类固醇治疗通常有效，但该病常以复发数年为特征。
