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逆行性肾内手术中肾下极结石移位可改善无结石状态:一项前瞻性随机对照试验

Displacement of Lower Pole Stones During Retrograde Intrarenal Surgery Improves Stone-free Status: A Prospective Randomized Controlled Trial.

作者信息

Yaghoubian Alan J, Anastos Harry, Khusid Johnathan A, Shimonov Roman, Lundon Dara J, Khargi Raymond, Gallante Blair, Gassmann Kyra, Bamberger Jacob N, Chandhoke Ryan, Zampini Anna, Atallah William, Gupta Mantu

机构信息

Department of Urology, Icahn School of Medicine at Mount Sinai, New York, New York.

Downstate Health and Sciences University, College of Medicine, Brooklyn, New York.

出版信息

J Urol. 2023 May;209(5):963-970. doi: 10.1097/JU.0000000000003199. Epub 2023 Feb 8.

Abstract

PURPOSE

Lower pole renal stones are associated with the lowest stone-free status of any location in the urinary tract during retrograde intrarenal surgery. Prior work has suggested displacing lower pole stones to a more accessible part of the kidney to improve stone-free status. We sought to prospectively compare the efficacy of laser lithotripsy in situ vs after displacement during retrograde intrarenal surgery for lower pole stones.

MATERIALS AND METHODS

Between July 2017 and May 2022 patients undergoing retrograde intrarenal surgery for lower pole stones were randomized into an in situ or displacement group. Demographics, comorbidities, and operative parameters were documented. Primary outcome was stone-free status, determined by combination of abdominal x-ray and renal ultrasound at 30-day follow-up. Secondary outcomes included operative time, 30-day complications, emergency department visits, and readmissions.

RESULTS

A total of 138 patients (69 per group) were enrolled and analyzed. Baseline characteristics were similar between groups. Stone-free status significantly favored the displacement group over the in situ group (95% vs 74%, = .003, n=62 in each group). Operative time, total laser energy usage, 30-day complications, and 30-day emergency department visits or hospital readmissions were similar between groups. On multivariate analysis only study group allocation was significantly associated with stone-free status ( = .024).

CONCLUSIONS

Basket displacement of lower pole stones results in a significantly higher stone-free status compared to in situ lithotripsy. The technique is simple, atraumatic, and requires no additional equipment costs and little additional operative time, making it a practical tool in the treatment of lower pole stones.

摘要

目的

在逆行肾内手术中,下极肾结石的无石率是尿路中所有部位中最低的。先前的研究表明,将下极结石移至肾脏更容易接近的部位可提高无石率。我们旨在前瞻性比较逆行肾内手术治疗下极结石时原位激光碎石术与移位后激光碎石术的疗效。

材料与方法

2017年7月至2022年5月期间,接受逆行肾内手术治疗下极结石的患者被随机分为原位组或移位组。记录人口统计学、合并症和手术参数。主要结局是无石状态,在30天随访时通过腹部X线和肾脏超声联合确定。次要结局包括手术时间、30天并发症、急诊就诊和再入院情况。

结果

共纳入138例患者(每组69例)并进行分析。两组的基线特征相似。无石状态移位组显著优于原位组(95%对74%,P = .003,每组n = 62)。两组之间的手术时间、总激光能量使用、30天并发症以及30天急诊就诊或住院再入院情况相似。多因素分析显示,仅研究组分配与无石状态显著相关(P = .024)。

结论

与原位碎石术相比,下极结石的篮筐移位导致显著更高的无石率。该技术简单、无创,无需额外设备成本且几乎不增加手术时间,使其成为治疗下极结石的实用工具。

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