Mendoza Rebecca R, Convertino Alexandra D, Blashill Aaron J
Department of Psychology, College of Sciences, San Diego State University, San Diego, California, USA.
San Diego State University/University of California San Diego Joint Doctoral Program in Clinical Psychology, San Diego, California, USA.
Int J Eat Disord. 2025 Apr;58(4):778-788. doi: 10.1002/eat.24370. Epub 2025 Jan 31.
Borderline personality disorder (BPD) and eating disorders (EDs) are common comorbid diagnoses. Given the various combinations of borderline personality disorder symptoms (BPDS) that can comprise a diagnosis, understanding whether specific BPDS are more likely to be associated with an ED (anorexia nervosa [AN], bulimia nervosa [BN], and binge eating disorder [BED]) is important for the conceptualization and treatment of BPD-ED comorbidity.
This study used data from the National Epidemiologic Survey on Alcohol and Related Conditions-III (NESARC-III) study, a nationally representative dataset of US adults (N = 36,309). The association of BPDS with EDs, compared with psychiatric and healthy control groups, was examined in two binomial and two multinomial (i.e., with all ED diagnoses) models.
Compared with the healthy control group, affect instability, emptiness, impulsivity, self-injurious behaviors, and unstable relationships were positively associated with any ED diagnosis (AN, BN, or BED). Compared with the psychiatric control group, impulsivity was positively associated with any ED diagnosis. In the multinomial model with the healthy control group, impulsivity and self-injurious behaviors were positively associated with AN, BN, and BED, emptiness was positively associated with AN and BED, and unstable relationships and affect instability were positively associated with BED. In the multinomial model with the psychiatric control group, self-injurious behaviors were positively associated with AN, and impulsivity and affect instability were positively associated with BED.
Results suggest certain BPDS may be more common with certain EDs (AN, BN, and BED), even when controlling for other EDs and a psychiatric control group.
边缘型人格障碍(BPD)和进食障碍(EDs)是常见的共病诊断。鉴于构成边缘型人格障碍诊断的症状(BPDS)有多种组合,了解特定的BPDS是否更有可能与进食障碍(神经性厌食症[AN]、神经性贪食症[BN]和暴饮暴食症[BED])相关,对于边缘型人格障碍与进食障碍共病的概念化和治疗很重要。
本研究使用了来自全国酒精及相关疾病流行病学调查-III(NESARC-III)研究的数据,这是一个具有全国代表性的美国成年人数据集(N = 36,309)。在两个二项式模型和两个多项(即所有进食障碍诊断)模型中,将BPDS与进食障碍的关联与精神科对照组和健康对照组进行了比较。
与健康对照组相比,情感不稳定、空虚感、冲动性、自我伤害行为和关系不稳定与任何进食障碍诊断(AN、BN或BED)呈正相关。与精神科对照组相比,冲动性与任何进食障碍诊断呈正相关。在与健康对照组的多项模型中,冲动性和自我伤害行为与AN、BN和BED呈正相关,空虚感与AN和BED呈正相关,关系不稳定和情感不稳定与BED呈正相关。在与精神科对照组的多项模型中,自我伤害行为与AN呈正相关,冲动性和情感不稳定与BED呈正相关。
结果表明,即使在控制了其他进食障碍和精神科对照组的情况下,某些BPDS可能在某些进食障碍(AN、BN和BED)中更常见。