Kapadia Avantika, Thornton Laura M, Munn-Chernoff Melissa A, Abramovitch Amitai, McKay Dean, Abramowitz Jonathan S, Yilmaz Zeynep, Crowley James J, Bulik Cynthia M, Watson Hunna J
Department of Psychological and Brain Sciences, University of Louisville, Louisville, KY, USA.
Department of Psychiatry, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
J Affect Disord. 2025 Apr 15;375:496-507. doi: 10.1016/j.jad.2025.01.068. Epub 2025 Jan 24.
OCD symptoms are well documented in anorexia nervosa (AN) and to a lesser extent in bulimia nervosa (BN), yet remain virtually unstudied in binge-eating disorder (BED).
In this cross-sectional observational study, 5927 participants with lifetime eating disorders (EDs) (i.e., past or current) were categorized into five groups based on their diagnostic histories: AN only (n = 2330), BN only (n = 740), BED only (n = 665), AN and another ED diagnosis (AN Mixed) (n = 1293), and BN and BED (BN-BED) (n = 899). Obsessive-Compulsive Inventory-12 scores were compared across these groups and with OCD (n = 1040), anxiety-related disorders (ANX) (n = 423), and non-clinical community (NCC) (n = 1194) cohorts.
OCD symptoms were common among individuals with lifetime AN, BN, BED, and multiple EDs, with obsessing being the most prevalent dimension, followed by ordering, checking, and washing. The obsessing scale, which captures general intrusive thoughts rather than traditional OCD obsessions, was notably high. ED groups generally scored higher on the OCI-12 subscales than the ANX and NCC cohorts but lower than the OCD cohort, although ordering severity was higher in some ED groups. Positive correlations were found between ED symptoms and OCI-12 subscales, and gender-diverse individuals and men had greater OCD symptoms than women.
Clinicians should be vigilant for OCD symptoms in individuals with AN, BN, and BED. These findings call for research on the mechanisms linking EDs and OCD symptoms and support integrated treatment approaches for both conditions.
强迫症症状在神经性厌食症(AN)中已有充分记录,在神经性贪食症(BN)中也有一定程度的记录,但在暴饮暴食症(BED)中几乎未被研究。
在这项横断面观察性研究中,5927名有终生饮食失调(即过去或当前)的参与者根据其诊断史被分为五组:仅患有AN(n = 2330)、仅患有BN(n = 740)、仅患有BED(n = 665)、AN与另一种饮食失调诊断(AN混合)(n = 1293)以及BN与BED(BN - BED)(n = 899)。对这些组以及强迫症(n = 1040)、焦虑相关障碍(ANX)(n = 423)和非临床社区(NCC)(n = 1194)队列的强迫观念量表 - 12得分进行了比较。
强迫症症状在患有终生AN、BN、BED和多种饮食失调的个体中很常见,其中强迫观念是最普遍的维度,其次是排序、检查和清洗。捕捉一般侵入性思维而非传统强迫症强迫观念的强迫观念量表得分显著较高。饮食失调组在OCI - 12子量表上的得分通常高于ANX和NCC队列,但低于强迫症队列,尽管在某些饮食失调组中排序严重程度更高。饮食失调症状与OCI - 12子量表之间存在正相关,性别多样化个体和男性的强迫症症状比女性更严重。
临床医生应对患有AN、BN和BED的个体中的强迫症症状保持警惕。这些发现呼吁对饮食失调与强迫症症状之间的联系机制进行研究,并支持针对这两种情况的综合治疗方法。