Naus A
J Hyg Epidemiol Microbiol Immunol. 1985;29(1):29-36.
The sense of smell has its meaning for a successful performance of certain occupations. It has further a protective meaning. The acuity of smell often changes for different reasons. The prolonged or repeated smelling is combined with the process of smell adaptation, fatigue and habituation. They diminish the flavour sensations and increase the risk of work accidents. Some chemical compounds are characterized by a quick and high adaptation. The occupational changes of smell can be peripheral or central. The qualitative changes of the smell perception are numerous, but they have little sense in industrial hygiene. The hypersensibilisation can be temporal or lasting, where a change of profession is sometimes inevitable. The values of smell thresholds (detection, recognition, distinction) of 25 substances are given. The sensitivity of smell is greater at the smell threshold concentrations. The smell thresholds are put among the main basic properties of chemical compounds which decide about the values of MAC and about the possibilities of their passing over. 68 substances ranged according to their basic characteristics in three groups were studied. There was statistical dependence between the molecular weight, the boiling point, smell thresholds of detection and recognition. In two groups of matters there was a dependence between the threshold of irritation and the smell threshold of recognition and distinction. The regression was linear with the majority of dependencies.
嗅觉对于某些职业的成功履职具有意义。它还具有保护意义。嗅觉敏锐度常因不同原因而改变。长时间或反复闻嗅会与嗅觉适应、疲劳和习惯化过程相关联。它们会减弱味觉感受并增加工作事故风险。一些化合物具有快速且高度的适应性。职业性嗅觉变化可能是外周性的或中枢性的。嗅觉感知的质性变化众多,但在工业卫生中意义不大。超敏反应可能是暂时的或持久的,有时不可避免地需要更换职业。给出了25种物质的嗅觉阈值(检测、识别、区分)值。在嗅觉阈值浓度下,嗅觉灵敏度更高。嗅觉阈值被列为决定最高容许浓度值及其通过可能性的化合物主要基本特性之一。对根据基本特征分为三组的68种物质进行了研究。分子量、沸点、检测和识别嗅觉阈值之间存在统计相关性。在两组物质中,刺激阈值与识别和区分嗅觉阈值之间存在相关性。大多数相关性的回归呈线性。