Sulis Daniel B, Lavoine Nathalie, Sederoff Heike, Jiang Xiao, Marques Barbara M, Lan Kai, Cofre-Vega Carlos, Barrangou Rodolphe, Wang Jack P
TreeCo, Raleigh, NC, USA.
Department of Forestry and Environmental Resources, North Carolina State University, Raleigh, NC, USA.
Nat Commun. 2025 Feb 1;16(1):1244. doi: 10.1038/s41467-025-56472-y.
Lignocellulose, an abundant renewable resource, presents a promising alternative for sustainable energy and industrial applications. However, large-scale adoption of lignocellulosic feedstocks faces considerable obstacles, including scalability, bioprocessing efficiency, and resilience to climate change. This Review examines current efforts and future opportunities for leveraging lignocellulosic feedstocks in bio-based energy and products, with a focus on enhancing conversion efficiency and scalability. It also explores emerging biotechnologies such as CRISPR-based genome editing informed by machine learning, aimed at improving feedstock traits and reducing the environmental impact of fossil fuel dependence.
木质纤维素是一种丰富的可再生资源,为可持续能源和工业应用提供了一个有前景的替代方案。然而,大规模采用木质纤维素原料面临着相当大的障碍,包括可扩展性、生物加工效率以及对气候变化的适应能力。本综述考察了目前在生物基能源和产品中利用木质纤维素原料的努力和未来机遇,重点是提高转化效率和可扩展性。它还探讨了新兴生物技术,如基于机器学习的CRISPR基因组编辑,旨在改善原料特性并减少对化石燃料依赖的环境影响。