来自九个不同人群的育龄妇女的破伤风抗毒素滴度。
Tetanus antitoxin titers in women of childbearing age from nine diverse populations.
作者信息
Varela L R, Black F L, Mendizabal-Morris C A
出版信息
J Infect Dis. 1985 May;151(5):850-3. doi: 10.1093/infdis/151.5.850.
The proportion of women with tetanus antitoxin titers adequate to provide protection for themselves and for their newborn infants varied from 96% in New Haven, Connecticut to 19% in Santiago, Chile. Women of childbearing age in five of the nine areas (São Paulo, Recife, and Pôrto Alegre, Brazil; Ecuador; and Gazankulu, South Africa) had an average of 40% immunity to tetanus and did not differ significantly from one another. By comparison with Chile, where vaccination during pregnancy is not current policy, we estimate that 21%-34% of the women in these five areas had received toxoid recently. In general about half the women with inadequate titer had undetectable levels of antibody and may require more than one dose of vaccine to attain immunity.
破伤风抗毒素滴度足以保护自身及其新生儿的女性比例，在康涅狄格州纽黑文为96%，在智利圣地亚哥则为19%。九个地区中的五个地区（巴西的圣保罗、累西腓和阿雷格里港；厄瓜多尔；以及南非的加赞库卢）的育龄妇女破伤风平均免疫率为40%，且彼此之间无显著差异。与智利（该国目前的政策是孕期不进行疫苗接种）相比，我们估计这五个地区21% - 34%的女性最近接种过类毒素。总体而言，大约一半滴度不足的女性抗体水平检测不到，可能需要接种一剂以上的疫苗才能获得免疫力。
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