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探索研究中的部分披露:伦理监督的挑战、理由及建议

Exploring Partial Disclosure in Research: Challenges, Justifications, and Recommendations for Ethical Oversight.

作者信息

Akuma Ifeanyichukwu, Vaswani Vina

机构信息

Center for Ethics, Yenepoya (Deemed to be University), Mangalore, Karnataka India.

出版信息

Asian Bioeth Rev. 2024 Oct 30;17(1):21-41. doi: 10.1007/s41649-024-00311-7. eCollection 2025 Jan.

Abstract

Deception in research is contentious, as ethical codes stress informed consent, yet complete disclosure may jeopardise validity. Indian Council for Medical Research (ICMR) guidelines classify deception into active, incomplete, and authorised forms. This study explores the ethical justification for incomplete (partial disclosure), permissible instances, and the dilemma faced by ethics committees in balancing scientific rigour and participant protection. The qualitative, non-experimental cross-sectional research, using in-depth interviews, identifies themes through thematic analysis. Findings reveal challenges for ethics committees, as incomplete information hampers understanding, amongst others. The paper proposes an ethics committee framework, urging researchers to minimise or avoid partial deception and recommending institutional awareness campaigns and standard operating procedures for minimal-harm studies using partial disclosure. Therefore, it proposes that partial disclosure should be justified by the 3Vs-value, validity, and veracity to preserve research integrity.

摘要

研究中的欺骗行为存在争议,因为伦理准则强调知情同意,但完全披露可能会损害研究的有效性。印度医学研究理事会(ICMR)的指南将欺骗行为分为主动、不完全和授权形式。本研究探讨了不完全披露(部分披露)的伦理依据、可允许的情况以及伦理委员会在平衡科学严谨性和保护参与者方面所面临的困境。这项定性的非实验性横断面研究采用深入访谈,通过主题分析确定主题。研究结果揭示了伦理委员会面临的挑战,比如不完全信息会妨碍理解等。本文提出了一个伦理委员会框架,敦促研究人员尽量减少或避免部分欺骗行为,并建议开展机构宣传活动以及针对使用部分披露的最小伤害研究制定标准操作程序。因此,本文提出部分披露应以3V(价值、有效性和真实性)来证明其合理性,以维护研究的完整性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/521a/11785864/eb71b2591c2a/41649_2024_311_Fig1_HTML.jpg

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