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一只比利时玛利诺犬的播散性感染。

Disseminated infection in a Belgian Malinois.

作者信息

Ringhofer J D, HIrsch E M, Michalak S R, Wiederhold N, Cañete-Gibas C, Dear J D

机构信息

Veterinary Medical Teaching Hospital, University of California, One Shields Avenue, Davis, CA, 95616, USA.

Fungus Testing Laboratory, Departments of Pathology & Laboratory Medicine, University of Texas Health Science Center at San Antonio, San Antonio, TX, 78229, USA.

出版信息

Med Mycol Case Rep. 2025 Jan 11;47:100692. doi: 10.1016/j.mmcr.2025.100692. eCollection 2025 Mar.

Abstract

We report disseminated mycosis in a Belgian Malinois caused by . The dog presented for progressive hindlimb weakness after diagnosis of suspected bacterial discospondylitis. Magnetic resonance imaging combined with radiographs revealed multifocal discospondylitis, osteomyelitis, and spondylitis with epidural empyema. was identified on culture and DNA sequencing of urine and fine needle aspirates of affected disc spaces. Aggressive therapy including amphotericin B liposomal complex, micafungin, and azoles were initiated, but the dog was euthanized seven months later due to progressive neurologic disease. This is the first report of disseminated disease by in veterinary medicine.

摘要

我们报告了一例比利时马林诺斯犬由 引起的播散性真菌病。这只狗在被诊断为疑似细菌性椎间盘炎后出现进行性后肢无力。磁共振成像结合X光片显示多灶性椎间盘炎、骨髓炎和脊柱炎伴硬膜外脓肿。在对受影响椎间盘间隙的尿液和细针抽吸物进行培养和DNA测序时鉴定出了 。开始了包括两性霉素B脂质体复合物、米卡芬净和唑类药物在内的积极治疗,但由于进行性神经疾病,这只狗在七个月后被安乐死。这是兽医医学中首例由 引起的播散性疾病报告。

需注意,原文中部分关键病因未明确写出具体内容,译文里保留了原文的占位表述。

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