Booth M J, van der Lugt J J, van Heerden A, Picard J A
Botha van der Lugt Veterinary Pathologists, Pretoria, South Africa.
J S Afr Vet Assoc. 2001 Jun;72(2):99-104. doi: 10.4102/jsava.v72i2.628.
Disseminated mycosis caused by Paecilomyces varioti in a female German shepherd dog presented with chronic forelimb lameness is described. Radiographs of the swollen carpal joint revealed geographic lysis of the radial epiphysis. Diagnosis was based on cytological demonstration of fungal hyphae and chlamydiospores, as well as fungal culture of fluid obtained by arthrocentesis. Temporary remission was characterised by markedly improved clinical signs and laboratory parameters, following treatment with ketoconazole. The dog was euthanased 9 months after the initial diagnosis, following the diagnosis of multifocal discospondylitis. This appears to be the longest described period of temporary remission obtained with treatment in dogs with paecilomycosis. Clinical, clinicopathological and necropsy findings of this disease in another German shepherd dog are briefly described.
描述了一只患有慢性前肢跛行的德国牧羊犬母犬由变幻拟青霉引起的播散性真菌病。肿胀腕关节的X线片显示桡骨骨骺呈地图状溶解。诊断基于真菌菌丝和厚壁孢子的细胞学证实，以及关节穿刺获得的液体的真菌培养。酮康唑治疗后，临床症状和实验室参数明显改善，出现暂时缓解。最初诊断9个月后，该犬因多灶性椎间盘炎被实施安乐死。这似乎是犬拟青霉病治疗后描述的最长的暂时缓解期。简要描述了另一只德国牧羊犬患此病的临床、临床病理和尸检结果。
