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大鼠模拟后30天脂肪填充与透明质酸填充剂注射的组织学比较

Histological Comparison of Lipofilling and Hyaluronic Acid Filler Injection 30 Days after Simulation in Rats.

作者信息

Lavrenteva E A, Khlystalov M V, Moroz S E, Hodorovich O S, Korolev A G, Ibadullaeva S S, Kastyro I V, Kartasheva A F, Ganshin I B, Barannik M I, Sarygin P V, Inozemtsev A N

机构信息

Peoples' Friendship University of Russia, Moscow, Russia.

Russian Research Center of Roentgenology and Radiology, Moscow, Russia.

出版信息

Dokl Biol Sci. 2025 Feb;520(1):44-48. doi: 10.1134/S0012496624600465. Epub 2025 Jan 31.

DOI:10.1134/S0012496624600465
PMID:39899240
Abstract

A histological comparison of lipofilling and hyaluronic acid filler injection was performed in rats. Studies at the histological level showed that, compared with hyaluronic acid filler injection, autologous fat grafting led to a more uniform distribution of adipose tissue at 30 days after treatment and a decrease in the area of sebaceous glands. Compared with lipofilling, the hyaluronic acid filler facilitated an increase in epidermis thickness because the granular layer and dermis grew thicker in addition to the filler injected into the subcutaneous space.

摘要

在大鼠身上进行了脂肪填充与透明质酸填充剂注射的组织学比较。组织学水平的研究表明,与透明质酸填充剂注射相比,自体脂肪移植在治疗后30天导致脂肪组织分布更均匀,皮脂腺面积减小。与脂肪填充相比,透明质酸填充剂使表皮厚度增加,因为除了注入皮下间隙的填充剂外,颗粒层和真皮也变厚了。

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