Shergujri Danish Ahmad, Khanday Murtaza Ahmad, Noor Aisha, Adnan Mohd, Arif Iqra, Raza Syed Naiem, Mir Reyaz Hassan, Khan Nisar Ahmad
Pharmaceutics Division, Department of Pharmaceutical Sciences, University of Kashmir, Hazratbal, Srinagar-190006, Jammu and Kashmir, India.
Department of Biology, College of Science, University of Ha'il, Ha'il, P.O. Box 2440, Saudi Arabia.
J Mater Chem B. 2025 Mar 5;13(10):3222-3244. doi: 10.1039/d4tb02068e.
Biopolymers or natural polymers like chitosan, cellulose, alginate, collagen, have gained significant interest recently due to their remarkable tunable properties that make them appropriate for a variety of applications & play a crucial role in everyday life. The features of biopolymers which include biodegradability, biocompatibility, sustainability, affordability, & availability are vital for creating products for use in biomedical fields. Apart from these characteristics, smart or stimuli-responsive biopolymers also show a distinctive property of being susceptible to various factors like pH, temperature, light intensity, & electrical or magnetic fields. The current review would present a brief idea about smart biopolymer gels along with their biomedical applications. The use of smart biopolymers gels as theranostic agents are also discussed in the present review. This review also focuses on the application of biopolymers in the fields of drug delivery, cancer treatment, tissue engineering & wound healing. These areas demonstrate the development and utilization of different types of biopolymers in current biomedical applications.
生物聚合物或天然聚合物，如壳聚糖、纤维素、藻酸盐、胶原蛋白，由于其具有显著的可调节特性，使其适用于各种应用，并在日常生活中发挥着至关重要的作用，因此最近受到了广泛关注。生物聚合物的特性包括生物降解性、生物相容性、可持续性、可承受性和可得性，这些特性对于制造用于生物医学领域的产品至关重要。除了这些特性外，智能或刺激响应性生物聚合物还表现出一种独特的性质，即易受pH值、温度、光强度以及电场或磁场等各种因素的影响。本综述将简要介绍智能生物聚合物凝胶及其生物医学应用。本综述还讨论了智能生物聚合物凝胶作为治疗诊断剂的用途。本综述还重点介绍了生物聚合物在药物递送、癌症治疗、组织工程和伤口愈合领域的应用。这些领域展示了不同类型生物聚合物在当前生物医学应用中的开发和利用。
