Aslam Khan Muhammad Umar, Abd Razak Saiful Izwan, Al Arjan Wafa Shamsan, Nazir Samina, Sahaya Anand T Joseph, Mehboob Hassan, Amin Rashid
Department of Polymer Engineering and Technology, University of the Punjab, Lahore 54590, Punjab, Pakistan.
School of Biomedical Engineering and Health Sciences, Faculty of Engineering, Universiti Teknologi Malaysia, Skudai 81300, Johor, Malaysia.
Molecules. 2021 Jan 25;26(3):619. doi: 10.3390/molecules26030619.
The polymeric composite material with desirable features can be gained by selecting suitable biopolymers with selected additives to get polymer-filler interaction. Several parameters can be modified according to the design requirements, such as chemical structure, degradation kinetics, and biopolymer composites' mechanical properties. The interfacial interactions between the biopolymer and the nanofiller have substantial control over biopolymer composites' mechanical characteristics. This review focuses on different applications of biopolymeric composites in controlled drug release, tissue engineering, and wound healing with considerable properties. The biopolymeric composite materials are required with advanced and multifunctional properties in the biomedical field and regenerative medicines with a complete analysis of routine biomaterials with enhanced biomedical engineering characteristics. Several studies in the literature on tissue engineering, drug delivery, and wound dressing have been mentioned. These results need to be reviewed for possible development and analysis, which makes an essential study.
通过选择合适的生物聚合物与选定的添加剂以实现聚合物-填料相互作用，可获得具有理想特性的聚合物复合材料。根据设计要求，可以修改几个参数，如化学结构、降解动力学和生物聚合物复合材料的机械性能。生物聚合物与纳米填料之间的界面相互作用对生物聚合物复合材料的机械特性具有重要控制作用。本综述重点关注生物聚合物复合材料在控释药物、组织工程和伤口愈合方面的不同应用，这些应用具有相当的特性。生物医学领域和再生医学需要具有先进和多功能特性的生物聚合物复合材料，并对具有增强生物医学工程特性的常规生物材料进行全面分析。文献中提到了一些关于组织工程、药物递送和伤口敷料的研究。这些结果需要进行审查，以进行可能的开发和分析，这是一项重要的研究。
