Bérubé Béatrice, Boidin Maxime, Gayda Mathieu, Vincent Thomas, Tremblay Jonathan, Juneau Martin, Nigam Anil, Karelis Antony D, Bherer Louis
Research Center and EPIC Center, Montreal Heart Institute, Montreal, Québec, Canada.
Research Center, Institut Universitaire de Gériatrie de Montréal, Montreal, Québec, Canada.
Physiol Rep. 2025 Feb;13(3):e70211. doi: 10.14814/phy2.70211.
The aim of this study was to measure the effects of chronic and acute aerobic exercise at two different intensities on cognitive performance and cerebrovascular response in coronary heart disease (CHD) patients. Thirty-five CHD patients completed two exercise bouts at 30% and 70% of their respective peak aerobic power on an ergocycle while performing cognitive tasks, which included nonexecutive and executive conditions before and after a 3-month training intervention. Variations of oxy- deoxy- and total hemoglobin concentrations were measured on the left prefrontal cortex at both intensities using near-infrared spectroscopy. Aerobic exercise training consisted of linear and nonlinear periodization protocols for three sessions of 30-50 min per week for 12 weeks. Error rate (p < 0.001) and reaction time (p < 0.001) improved after the training program for the executive condition of the cognitive task, regardless of intensity and training groups. Cerebral oxygenation remained similar pre and post intervention for all conditions and acute exercise intensity. Despite the absence of conjunction between cerebral oxygenation and cognition, results suggest that both exercise training programs could improve cognition in CHD patients during acute exercise.
本研究的目的是测量两种不同强度的慢性和急性有氧运动对冠心病(CHD)患者认知能力和脑血管反应的影响。35名冠心病患者在进行认知任务时,在测力计上以各自峰值有氧功率的30%和70%完成了两轮运动,这些认知任务包括在为期3个月的训练干预前后的非执行和执行条件。使用近红外光谱法在两种强度下测量左前额叶皮层的氧合血红蛋白、脱氧血红蛋白和总血红蛋白浓度的变化。有氧运动训练包括线性和非线性周期化方案,每周进行三次,每次30 - 50分钟,共12周。无论强度和训练组如何,在认知任务的执行条件下,训练计划后错误率(p < 0.001)和反应时间(p < 0.001)均有所改善。在所有条件和急性运动强度下,干预前后的脑氧合情况保持相似。尽管脑氧合与认知之间没有关联,但结果表明,两种运动训练方案都可以改善冠心病患者在急性运动期间的认知能力。