Kramer E L, McLaws R, Sanger J J, Shaw W
Microsurgery. 1985;6(1):40-5. doi: 10.1002/micr.1920060108.
The sequence of scintigraphic patterns in resolving lymphedema in the replanted hind limb of the rat is reported. Compared to simple observation of the limb, scintigraphy using 99mTc-antimony trisulfide colloid (99mTc SbSC) provides multiple qualitative parameters for assessing lymphedema, ie, diffuse uptake in the implanted limb, focal uptake at the site of surgical repair, accumulation in the popliteal node, and activity in the liver. Quantitative analysis in this model was not helpful. Scintigraphic criteria may be utilized to study the effect of alteration in the animal model described. It is hoped that this model can be used to clarify the clinical factors influencing the resolution of lymphedema.
本文报道了大鼠后肢再植后淋巴水肿消退过程中的闪烁扫描图像序列。与单纯观察肢体相比，使用99mTc-硫化锑胶体（99mTc SbSC）进行闪烁扫描可为评估淋巴水肿提供多个定性参数，即植入肢体的弥漫性摄取、手术修复部位的局灶性摄取、腘窝淋巴结的积聚以及肝脏的活性。该模型中的定量分析并无帮助。闪烁扫描标准可用于研究上述动物模型中改变的影响。希望该模型能够用于阐明影响淋巴水肿消退的临床因素。
