Hosseini Maryam, Houjaghan Amirmasoud Kazemzadeh, Behzad Ghazal, Ghorbanpour Sahar, Razavi Seyede Zahra Emami, Azadvari Mohaddeseh, Movaseghi Shafieh, Salaminour Negar
Department of Physical Medicine and Rehabilitation Imam Khomeini Hospital Complex, Tehran University of Medical Sciences Tehran Iran.
Department of Internal Medicine Imam Khomeini Hospital Complex, Tehran University of Medical Sciences Tehran Iran.
Health Sci Rep. 2025 Feb 3;8(2):e70417. doi: 10.1002/hsr2.70417. eCollection 2025 Feb.
Ankylosing spondylitis (AS) is a chronic inflammatory disease that affects quality of life (QoL) due to its impact on physical and emotional well-being. Accurate and reliable tools are needed to assess disease activity and QoL in different cultural contexts. This study aimed to evaluate the psychometric properties of the Persian versions of the Evaluation of Ankylosing Spondylitis Quality of Life (EASi-QoL) and Ankylosing Spondylitis Disease Activity Score (ASDAS) scales in Iranian AS patients.
A cross-sectional study was conducted on 70 AS patients referred to a tertiary hospital in Tehran. Patients completed the EASi-QoL, and 39 also completed the ASDAS questionnaire. The translation followed the forward-backward method. Reliability was assessed using Cronbach's for internal consistency and intraclass correlation coefficient (ICC) for test-retest reliability. Content validity was evaluated using the content validity ratio (CVR) and Content Validity Index (CVI). Test-retest reliability was examined using Spearman's rank correlation for non-normally distributed data.
The ICC values for EASi-QoL ranged from 0.71 to 0.82, while Spearman's correlation coefficients ranged from 0.63 to 0.80. For ASDAS, all items except Question 1 had ICC and Spearman's correlation coefficients above 0.8, indicating high test-retest reliability. The average CVR for EASi-QoL was 0.56, and for ASDAS it was 0.68. The CVI for relevance, clarity, and simplicity ranged from 0.86 to 0.96 for both scales, confirming good content validity.
The Persian versions of the EASi-QoL and ASDAS scales demonstrate adequate reliability and validity. These tools are suitable for assessing QoL and disease activity in Iranian AS patients, providing culturally relevant measurements for clinical and research settings.
强直性脊柱炎（AS）是一种慢性炎症性疾病，因其对身体和情绪健康的影响而影响生活质量（QoL）。在不同文化背景下，需要准确可靠的工具来评估疾病活动度和生活质量。本研究旨在评估伊朗强直性脊柱炎患者中波斯语版强直性脊柱炎生活质量评估量表（EASi-QoL）和强直性脊柱炎疾病活动度评分（ASDAS）量表的心理测量特性。
对转诊至德黑兰一家三级医院的70例强直性脊柱炎患者进行了横断面研究。患者完成了EASi-QoL量表，其中39例还完成了ASDAS问卷。翻译采用前后翻译法。使用Cronbach's α系数评估内部一致性的信度，使用组内相关系数（ICC）评估重测信度。使用内容效度比（CVR）和内容效度指数（CVI）评估内容效度。对于非正态分布的数据，使用Spearman等级相关性检验重测信度。
EASi-QoL量表的ICC值范围为0.71至0.82，而Spearman相关系数范围为0.63至0.80。对于ASDAS量表，除问题1外，所有项目的ICC和Spearman相关系数均高于0.8，表明重测信度高。EASi-QoL量表的平均CVR为0.56，ASDAS量表为0.68。两个量表在相关性、清晰度和简单性方面的CVI范围为0.86至0.96，证实了良好的内容效度。
波斯语版的EASi-QoL和ASDAS量表显示出足够的信度和效度。这些工具适用于评估伊朗强直性脊柱炎患者中的生活质量和疾病活动度，为临床和研究环境提供与文化相关的测量方法。
