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马蹄肾合并肾细胞癌:一例报告。

Renal cell carcinoma in a horseshoe kidney: A case report.

作者信息

Chaker Kays, Gharbia Nader, Ouanes Yassine, Zehani Alia, Mosbahi Boutheina, Nouira Yassine

机构信息

Department of Urology, La Rabta Hospital, University of Tunis El Manar, Tunis, Tunisia.

Department of Urology, La Rabta Hospital, University of Tunis El Manar, Tunis, Tunisia.

出版信息

Int J Surg Case Rep. 2025 Mar;128:111015. doi: 10.1016/j.ijscr.2025.111015. Epub 2025 Feb 4.

DOI:10.1016/j.ijscr.2025.111015
PMID:39914014
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11847545/
Abstract

BACKGROUND

Horseshoe kidneys are often considered a typical and frequently occurring type of kidney fusion anomaly when compared to other anomalies. Surgery for tumors that appear in horseshoe kidneys can challenging due to the abnormal vasculature and the potential need for isthmectomy. In such cases, open surgery remains a viable treatment option.

CASE PRESENTATION

A 65-year-old African male patient hospitalized for total hematuria evolving for 6 months, and right lumbar pain without fever. The patient underwent a computed tomography scan, which revealed the presence of a solid mass occupying the junction of the isthmus and the inferior pole of left renal of a horseshoe kidney wish measured 30 mm. Tumorectomy was done by open lobotomy. The histological examination of the surgical specimen showed the presence of a clear cell carcinoma of the left kidney. After 52 months of clinical and radiological check-up, there was no functional complaint or any sign of recurrence.

DISCUSSION

Horseshoe kidneys are the most common fusion anomaly. These patients have an increased risk of malignant tumors, including renal cell carcinoma. Many studies indicate that horseshoe kidney tumors can be treated with partial nephrectomy, if feasible, with generally acceptable morbidity.

CONCLUSION

This report presents a successful case where open surgery was used to partially remove a horseshoe kidney affected by renal carcinoma. We believe that, in certain circumstances, such as the presence of complex vascularization or an unfavorably located tumor, open surgery remains a reliable option for nephron-sparing procedures.

摘要

背景

与其他肾脏异常相比,马蹄肾通常被认为是一种典型且常见的肾脏融合异常类型。由于马蹄肾血管异常以及可能需要进行峡部切除术,对马蹄肾中出现的肿瘤进行手术具有挑战性。在这种情况下,开放手术仍然是一种可行的治疗选择。

病例报告

一名65岁的非洲男性患者因持续6个月的全程血尿和右侧腰痛入院,无发热症状。患者接受了计算机断层扫描,结果显示在马蹄肾左肾峡部与下极交界处有一个实性肿块,大小为30毫米。通过开放性肾叶切除术进行了肿瘤切除。手术标本的组织学检查显示为左肾透明细胞癌。经过52个月的临床和影像学检查,患者无功能方面的不适,也没有复发迹象。

讨论

马蹄肾是最常见的融合异常。这些患者患恶性肿瘤(包括肾细胞癌)的风险增加。许多研究表明,如果可行,马蹄肾肿瘤可以通过部分肾切除术进行治疗,总体发病率可接受。

结论

本报告展示了一例成功的病例,即通过开放手术部分切除了患有肾癌的马蹄肾。我们认为,在某些情况下,如存在复杂血管情况或肿瘤位置不佳时,开放手术仍然是保留肾单位手术的可靠选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842f/11847545/11c0ef6039bb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842f/11847545/bab4a41c1f30/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842f/11847545/b7584826395a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842f/11847545/11c0ef6039bb/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842f/11847545/bab4a41c1f30/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842f/11847545/b7584826395a/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/842f/11847545/11c0ef6039bb/gr3.jpg

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本文引用的文献

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Clin Case Rep. 2023 Oct 29;11(11):e8116. doi: 10.1002/ccr3.8116. eCollection 2023 Nov.
2
Renal Cell Carcinoma Arising from Isthmus of Horseshoe K.马蹄肾峡部起源的肾细胞癌
J Kidney Cancer VHL. 2023 May 2;10(2):1-7. doi: 10.15586/jkcvhl.v10i2.267. eCollection 2023.
3
The SCARE 2023 guideline: updating consensus Surgical CAse REport (SCARE) guidelines.
SCARE 2023 指南:更新共识外科病例报告(SCARE)指南。
Int J Surg. 2023 May 1;109(5):1136-1140. doi: 10.1097/JS9.0000000000000373.
4
Wilms' Tumor in Horseshoe Kidney.马蹄肾中的肾母细胞瘤
Case Rep Nephrol Dial. 2021 Jun 17;11(2):124-128. doi: 10.1159/000514774. eCollection 2021 May-Aug.
5
Laparoscopic nephron-sparing surgery for a tumor near the isthmus of a horseshoe kidney with a complicated blood supply.马蹄肾峡部附近肿瘤伴复杂血供的腹腔镜肾部分切除术。
J Int Med Res. 2020 Jun;48(6):300060520926736. doi: 10.1177/0300060520926736.
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Horseshoe kidney and associated anomalies: Single institutional review of 20 cases.马蹄肾及相关异常:20例单机构回顾性研究
Afr J Paediatr Surg. 2018 Apr-Jun;15(2):104-107. doi: 10.4103/ajps.AJPS_55_17.
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Surgical Treatment of Tumors Involving Kidneys With Fusion Anomalies: A Contemporary Series.涉及融合异常肾脏肿瘤的外科治疗:当代系列研究
Urology. 2016 Dec;98:97-102. doi: 10.1016/j.urology.2016.07.034. Epub 2016 Aug 3.
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Laparoscopic partial nephrectomy for renal cell carcinoma in a horseshoe kidney.马蹄肾肾细胞癌的腹腔镜下部分肾切除术
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