Johnson S, McAnerney J M, Schoub B D, Kidd A H
S Afr Med J. 1985 May 4;67(18):721-3.
A study was undertaken to determine the level of immunity to rubella in the population on the basis of findings in serum specimens sent to the laboratory of the National Institute for Virology. A total of 4791 sera taken between August 1982 and October 1983 were examined for rubella-specific IgG antibodies by enzyme-linked immunosorbent assay (ELISA). A disquietingly high proportion (18,4%) of women of child-bearing age were not immune; 59 cases of primary infection occurred in pregnant women, as documented by the presence of rubella-specific IgM antibodies on ELISA. The need to ensure the protection of susceptible women of child-bearing age by prepubertal immunization and screening for immunity is emphasized.
根据送往国家病毒学研究所实验室的血清标本检测结果，开展了一项研究以确定人群中的风疹免疫水平。通过酶联免疫吸附测定法（ELISA）对1982年8月至1983年10月期间采集的4791份血清进行了风疹特异性IgG抗体检测。育龄妇女中未具免疫力的比例高得令人不安（18.4%）；ELISA检测显示风疹特异性IgM抗体阳性，记录到59例孕妇发生原发性感染。强调了通过青春期前免疫和免疫筛查来确保保护易感育龄妇女的必要性。
