Center for Rehabilitation Sciences Research, Henry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Applied Physics Laboratory, Johns Hopkins University, Laurel, MD, USA.
Sci Rep. 2021 Jan 13;11(1):954. doi: 10.1038/s41598-020-79581-8.
Individuals with upper extremity (UE) amputation abandon prostheses due to challenges with significant device weight-particularly among myoelectric prostheses-and limited device dexterity, durability, and reliability among both myoelectric and body-powered prostheses. The Modular Prosthetic Limb (MPL) system couples an advanced UE prosthesis with a pattern recognition paradigm for intuitive, non-invasive prosthetic control. Pattern recognition accuracy and functional assessment-Box & Blocks (BB), Jebsen-Taylor Hand Function Test (JHFT), and Assessment of Capacity for Myoelectric Control (ACMC)-scores comprised the main outcomes. 10 participants were included in analyses, including seven individuals with traumatic amputation, two individuals with congenital limb absence, and one with amputation secondary to malignancy. The average (SD) time since limb loss, excluding congenital participants, was 85.9 (59.5) months. Participants controlled an average of eight motion classes compared to three with their conventional prostheses. All participants made continuous improvements in motion classifier accuracy, pathway completion efficiency, and MPL manipulation. BB and JHFT improvements were not statistically significant. ACMC performance improved for all participants, with mean (SD) scores of 162.6 (105.3), 213.4 (196.2), and 383.2 (154.3), p = 0.02 between the baseline, midpoint, and exit assessments, respectively. Feedback included lengthening the training period to further improve motion classifier accuracy and MPL control. The MPL has potential to restore functionality to individuals with acquired or congenital UE loss.
上肢截肢者因器械重量大（尤其是肌电假肢）、器械灵活性、耐用性和可靠性有限而放弃假肢-特别是肌电假肢和身体驱动假肢。模块化假肢（MPL）系统将先进的上肢假肢与模式识别范式相结合，实现直观、非侵入性的假肢控制。模式识别准确性和功能评估-方块和块（BB）、Jebsen-Taylor 手功能测试（JHFT）和肌电控制能力评估（ACMC）-评分构成了主要结果。10 名参与者被纳入分析，包括 7 名创伤性截肢者、2 名先天性肢体缺失者和 1 名因恶性肿瘤截肢者。除先天性参与者外，肢体丧失的平均（SD）时间为 85.9（59.5）个月。与传统假肢相比，参与者平均控制了 8 个运动类，而不是 3 个。所有参与者的运动分类器准确性、路径完成效率和 MPL 操作都有持续的提高。BB 和 JHFT 的改善没有统计学意义。所有参与者的 ACMC 表现都有所提高，平均（SD）得分分别为 162.6（105.3）、213.4（196.2）和 383.2（154.3），基线、中点和出口评估之间的 p 值分别为 0.02。反馈包括延长培训期，以进一步提高运动分类器的准确性和 MPL 的控制能力。MPL 有可能恢复后天或先天性上肢丧失功能的个体的功能。
