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Role of Microglia in Glaucomatous Pathology.小胶质细胞在青光眼病理中的作用。
Adv Exp Med Biol. 2025;1468:149-153. doi: 10.1007/978-3-031-76550-6_25.
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Microglia: Friends or Foes in Glaucoma? A Developmental Perspective.小胶质细胞：青光眼的朋友还是敌人？从发育角度看。
Stem Cells Transl Med. 2022 Dec 30;11(12):1210-1218. doi: 10.1093/stcltm/szac077.
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Retinal ganglion cell loss is accompanied by antibody depositions and increased levels of microglia after immunization with retinal antigens.免疫视网膜抗原后，视网膜神经节细胞丢失伴随着抗体沉积和小胶质细胞水平升高。
PLoS One. 2012;7(7):e40616. doi: 10.1371/journal.pone.0040616. Epub 2012 Jul 26.
4
Induced autoimmunity to heat shock proteins elicits glaucomatous loss of retinal ganglion cell neurons via activated T-cell-derived fas-ligand.诱导产生针对热休克蛋白的自身免疫，通过活化的T细胞衍生的Fas配体引发视网膜神经节细胞神经元的青光眼性丧失。
J Neurosci. 2008 Nov 12;28(46):12085-96. doi: 10.1523/JNEUROSCI.3200-08.2008.
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Microglial cGAS-STING signaling underlies glaucoma pathogenesis.小胶质细胞 cGAS-STING 信号通路在青光眼发病机制中起关键作用。
Proc Natl Acad Sci U S A. 2024 Sep 3;121(36):e2409493121. doi: 10.1073/pnas.2409493121. Epub 2024 Aug 27.
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Adoptive transfer of immune cells from glaucomatous mice provokes retinal ganglion cell loss in recipients.从青光眼小鼠中过继转移免疫细胞会引发受体的视网膜神经节细胞丢失。
Acta Neuropathol Commun. 2015 Sep 15;3:56. doi: 10.1186/s40478-015-0234-y.
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Time-dependent retinal ganglion cell loss, microglial activation and blood-retina-barrier tightness in an acute model of ocular hypertension.高眼压急性模型中视网膜神经节细胞的时间依赖性丢失、小胶质细胞激活及血视网膜屏障紧密性
Exp Eye Res. 2015 Jul;136:59-71. doi: 10.1016/j.exer.2015.05.010. Epub 2015 May 20.
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Autoreactive antibodies and loss of retinal ganglion cells in rats induced by immunization with ocular antigens.免疫眼部抗原诱导大鼠的自身反应性抗体和视网膜神经节细胞丢失。
Invest Ophthalmol Vis Sci. 2011 Nov 11;52(12):8835-48. doi: 10.1167/iovs.10-6889.
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Activation of Adenosine A Receptor Inhibits Microglia Reactivity Elicited by Elevated Pressure.腺苷 A 受体的激活抑制了由高压引起的小胶质细胞反应。
Int J Mol Sci. 2020 Sep 30;21(19):7218. doi: 10.3390/ijms21197218.
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The pathogenesis of glaucoma in the interplay with the immune system.青光眼在与免疫系统相互作用中的发病机制。
Invest Ophthalmol Vis Sci. 2013 Mar 28;54(3):2393-409. doi: 10.1167/iovs.12-9781.
本文引用的文献
1
A magneto-activated nanoscale cytometry platform for molecular profiling of small extracellular vesicles.一种用于小细胞外囊泡分子分析的磁激活纳米级细胞仪平台。
Nat Commun. 2023 Sep 11;14(1):5576. doi: 10.1038/s41467-023-41285-8.
2
Time-resolved assessment of single-cell protein secretion by sequencing.通过测序对单细胞蛋白质分泌进行时间分辨评估。
Nat Methods. 2023 May;20(5):723-734. doi: 10.1038/s41592-023-01841-y. Epub 2023 Apr 10.
3
Microglia depletion exacerbates retinal ganglion cell loss in a mouse model of glaucoma.小胶质细胞耗竭加剧青光眼小鼠模型中的视网膜神经节细胞丢失。
Exp Eye Res. 2022 Dec;225:109273. doi: 10.1016/j.exer.2022.109273. Epub 2022 Oct 4.
4
Remodeling of the Lamina Cribrosa: Mechanisms and Potential Therapeutic Approaches for Glaucoma.筛板重塑：青光眼的潜在治疗方法及机制。
Int J Mol Sci. 2022 Jul 22;23(15):8068. doi: 10.3390/ijms23158068.
5
An introduction to spatial transcriptomics for biomedical research.空间转录组学在生物医学研究中的应用简介。
Genome Med. 2022 Jun 27;14(1):68. doi: 10.1186/s13073-022-01075-1.
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Damage-Associated Molecular Patterns (DAMPs) in Retinal Disorders.损伤相关分子模式（DAMPs）在视网膜疾病中的作用。
Int J Mol Sci. 2022 Feb 26;23(5):2591. doi: 10.3390/ijms23052591.
7
Interplay between Müller cells and microglia aggravates retinal inflammatory response in experimental glaucoma.Müller 细胞与小胶质细胞的相互作用加剧了实验性青光眼的视网膜炎症反应。
J Neuroinflammation. 2021 Dec 24;18(1):303. doi: 10.1186/s12974-021-02366-x.
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Comparative Review of Microglia and Monocytes in CNS Phagocytosis.中枢神经系统吞噬作用中小胶质细胞和单核细胞的比较综述
Cells. 2021 Sep 27;10(10):2555. doi: 10.3390/cells10102555.
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Extracellular Matrix Remodeling in the Retina and Optic Nerve of a Novel Glaucoma Mouse Model.新型青光眼小鼠模型视网膜和视神经中的细胞外基质重塑
Biology (Basel). 2021 Feb 24;10(3):169. doi: 10.3390/biology10030169.
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Inflammation in Glaucoma: From the back to the front of the eye, and beyond.青光眼的炎症：从眼睛的后部到前部，以及更远的地方。
Prog Retin Eye Res. 2021 Jul;83:100916. doi: 10.1016/j.preteyeres.2020.100916. Epub 2020 Oct 17.
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