Gerstoft J, Nielsen J O, Dickmeiss E, Rønne T, Platz P, Mathiesen L
Acta Med Scand. 1985;217(2):213-24.
Twenty Danish patients with the acquired immunodeficiency syndrome (AIDS) had been diagnosed by January 1984, 14 of them after 1982. Eighteen patients were male homosexuals, 8 of whom had visited the USA after 1979, 2 were heterosexual males with a history of sexual contacts in Central Africa, suggesting a transmission of AIDS from woman to man. AIDS has not been observed in drug abusers, hemophiliacs or transfused non-risk persons in Denmark. The clinical picture varied according to the presence of Kaposi sarcoma or the type of opportunistic infections, but was in general similar to that reported from the USA. Investigation of T-lymphocyte subsets revealed that the AIDS patients differed from controls and healthy homosexual men by having either a very low number of helper cells or a low helper/suppressor cell ratio. Functional immunological studies revealed a decreased natural killer cell activity and decreased blast transformation by mitogens. The survival two years after diagnosis was 16%.
截至1984年1月，丹麦已确诊20例获得性免疫缺陷综合征（艾滋病）患者，其中14例是在1982年之后确诊的。18例患者为男性同性恋者，其中8例在1979年之后去过美国，2例是有中非性接触史的异性恋男性，提示存在艾滋病由女性传染给男性的情况。在丹麦，尚未在药物滥用者、血友病患者或接受输血的无风险人群中观察到艾滋病。临床症状根据是否存在卡波西肉瘤或机会性感染的类型而有所不同，但总体上与美国报告的情况相似。对T淋巴细胞亚群的调查显示，艾滋病患者与对照组及健康同性恋男性不同，其辅助细胞数量极少或辅助/抑制细胞比值较低。功能性免疫学研究显示自然杀伤细胞活性降低，有丝分裂原刺激后的母细胞转化能力下降。确诊后两年的生存率为16%。
