Roy Ayan, Patel Deepika, Merugu Chandhana, Kamalanathan Sadishkumar, Sahoo Jayaprakash, Naik Dukhabandhu
Endocrinology and Metabolism, AIIMS Kalyani, Kalyani, West Bengal 741245, India.
Continental Hospitals, Hyderabad, Telangana 500032, India.
JCEM Case Rep. 2025 Feb 10;3(3):luaf024. doi: 10.1210/jcemcr/luaf024. eCollection 2025 Mar.
The endocrine and cardiology interface is particularly interesting and important. This is a case series of 3 endocrine diseases presenting with acute myocardial infarction without obstructive coronary arterial diseases (MINOCA). The diagnosis was Cushing's disease due to pituitary microadenoma, adrenal pheochromocytoma, and primary hyperaldosteronism due to unilateral adrenal hyperplasia. All patients were managed conservatively and improved considerably following the management of underlying endocrine and cardiovascular diseases. A spectrum of classical endocrine diseases can present with MINOCA, and the underlying diagnosis is often overlooked. Patients without traditional risk factors for MINOCA should undergo hormonal workup to reveal the underlying diagnosis.
内分泌与心脏病学的交叉领域尤为引人关注且至关重要。这是一组3例内分泌疾病的病例系列,这些疾病均表现为无阻塞性冠状动脉疾病的急性心肌梗死(MINOCA)。诊断结果分别为垂体微腺瘤所致的库欣病、肾上腺嗜铬细胞瘤以及单侧肾上腺增生所致的原发性醛固酮增多症。所有患者均接受了保守治疗,在对潜在的内分泌和心血管疾病进行治疗后病情有了显著改善。一系列典型的内分泌疾病都可能表现为MINOCA,而潜在的诊断往往被忽视。没有MINOCA传统危险因素的患者应进行激素检查以明确潜在诊断。