Peterson Gregory M, Byrne Karen, Dillon Tae, Naguy Ahmed, Turnier-Shea Yvonne, Rybak Marzena, Pridmore Saxby
Peterson, PhD, MBA, School of Pharmacy and Pharmacology, University of Tasmania, Hobart, Australia.
Byrne, RN, Hobart Transcranial Magnetic Stimulation (TSM), Bellerive, Tasmania, Australia.
Psychopharmacol Bull. 2025 Feb 3;55(2):100-103.
A patient with major depressive disorder (MDD) was receiving transcranial magnetic stimulation (TMS). A little over halfway through the course the patient was bereaved and experienced normal sadness. Our objective is to describe the tracking and outcome of this common emotionally distressing event.
Routine assessments conducted at the centre include the six-item Hamiton depression rating (HAMD6) scale, the Clinical Global Impression-Severity (CGI-S) scale, and the Subjective Depression Scale (SDS6). In addition, the Daily Sadness Scale (DSS) is applied at each treatment day; this is a single question asking how much sadness/depression is being experienced.
On the 19th treatment day, the patient was bereaved and experienced appropriate sadness. The pathological state (MDD) resolved, as reflected by changes in the psychometric tools. Following the death, normal sadness emerged and lessened over a few weeks.
This case illustrates that while TMS can effectively treat MDD, it does not prevent the emergence of sadness in uncomplicated bereavement.
一名重度抑郁症（MDD）患者正在接受经颅磁刺激（TMS）治疗。在疗程进行到一半多一点的时候，患者遭遇了丧亲之痛并经历了正常的悲伤情绪。我们的目的是描述这一常见的情绪困扰事件的追踪情况及结果。
该中心进行的常规评估包括六项汉密尔顿抑郁评定量表（HAMD6）、临床总体印象-严重程度量表（CGI-S）和主观抑郁量表（SDS6）。此外，在每个治疗日使用每日悲伤量表（DSS）；这是一个单一问题，询问患者正在经历多少悲伤/抑郁情绪。
在第19个治疗日，患者遭遇丧亲之痛并经历了适当的悲伤情绪。心理测量工具的变化反映出病理状态（MDD）得到缓解。在亲人去世后，正常的悲伤情绪出现，并在几周内减轻。
该病例表明，虽然TMS可以有效治疗MDD，但它并不能防止在单纯的丧亲之痛中出现悲伤情绪。
