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急性流行性结膜炎的临床特征与流行病学洞察:印度中北部的一项多中心横断面研究

Clinical Features and Epidemiological Insights of Acute Epidemic Conjunctivitis: A Multicentric Cross-Sectional Study in North Central India.

作者信息

Aishwarya Ankita, Agarwal Amit, Saxena Deepti, Jain Vaibhav, Singh Adarsh, Agarwal Rachna

机构信息

Department of Ophthalmology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow.

Agarwal Netralaya, Aishbagh, D.A.V College Market, Lucknow.

出版信息

Rom J Ophthalmol. 2024 Oct-Dec;68(4):372-378. doi: 10.22336/rjo.2024.68.

DOI:10.22336/rjo.2024.68
PMID:39936060
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11809833/
Abstract

PURPOSE

To gain epidemiological insights by investigating the age, risk factors, and clinical features of individuals affected by the conjunctivitis outbreak.

METHODS

The study was conducted at various ophthalmic centers, involving participants with clinical symptoms of acute conjunctivitis within one week from 15 June 2024 to 15 July 2024. Demographic information, clinical features, signs, and symptoms were recorded and analyzed using SPSS version 21.0 and MedCalc software.

RESULTS

The study included 920 patients (1722 eyes), 56% males and 44% females, and most cases were bilateral (94%). Among the affected groups, hospital staff (43%) were the most affected, followed by school-going children (31%), those in direct contact with infected individuals (17%), or others (11%). The median age of onset was 26 years, with a range spanning from 2 to 76 years. The age group most affected was 19-49 years (52%), followed by <18 years (34%) and the elderly group (14%). The most common and first symptom was foreign body sensation (92%), and additional symptoms included ocular itching (81%) and watering (80%). The most prevalent signs were conjunctival congestion (99%), follicles (96%), subconjunctival bleeding (43%), eyelid swelling (51%), chemosis (39%), and pre-auricular lymph node enlargement (6%). Corneal involvement was not observed.

DISCUSSIONS

Acute Epidemic Conjunctivitis (AEC) outbreaks have significant implications for public health, particularly regarding healthcare resource utilization, economic burden, and disruption of daily life. Timely identification, effective communication, and coordinated response strategies are essential to managing AEC outbreaks and preventing their escalation.

CONCLUSION

This study provides crucial insights into epidemic conjunctivitis in North Central India. The study findings can guide targeted interventions and healthcare resource allocation to manage the outbreak effectively.

摘要

目的

通过调查受结膜炎暴发影响的个体的年龄、危险因素和临床特征,获取流行病学见解。

方法

该研究在多个眼科中心进行,纳入了2024年6月15日至2024年7月15日一周内有急性结膜炎临床症状的参与者。使用SPSS 21.0版和MedCalc软件记录并分析人口统计学信息、临床特征、体征和症状。

结果

该研究纳入了920名患者(1722只眼),男性占56%,女性占44%,大多数病例为双侧患病(94%)。在受影响的群体中,医院工作人员受影响最大(43%),其次是学龄儿童(31%)、与感染者直接接触的人(17%)或其他人群(11%)。发病的中位年龄为26岁,范围从2岁至76岁。受影响最严重的年龄组为19 - 49岁(52%),其次是<18岁(34%)和老年组(14%)。最常见的首发症状是异物感(92%),其他症状包括眼部瘙痒(81%)和流泪(80%)。最常见的体征是结膜充血(99%)、滤泡(96%)、结膜下出血(43%)、眼睑肿胀(51%)、球结膜水肿(39%)和耳前淋巴结肿大(6%)。未观察到角膜受累情况。

讨论

急性流行性结膜炎(AEC)暴发对公共卫生有重大影响,特别是在医疗资源利用、经济负担和日常生活干扰方面。及时识别、有效沟通和协调应对策略对于管理AEC暴发并防止其升级至关重要。

结论

本研究为印度中北部的流行性结膜炎提供了关键见解。研究结果可指导有针对性的干预措施和医疗资源分配,以有效管理此次暴发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b08d/11809833/d45972255bdd/RomJOphthalmol-68-372-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b08d/11809833/016a99bb8c74/RomJOphthalmol-68-372-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b08d/11809833/d45972255bdd/RomJOphthalmol-68-372-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b08d/11809833/016a99bb8c74/RomJOphthalmol-68-372-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b08d/11809833/d45972255bdd/RomJOphthalmol-68-372-g002.jpg

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本文引用的文献

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Madras eye outbreak in India: Why should we foster a better understanding of acute conjunctivitis?印度马德拉斯眼部疾病爆发:我们为何要加深对急性结膜炎的了解?
Indian J Ophthalmol. 2023 May;71(5):2298-2299. doi: 10.4103/IJO.IJO_3317_22.
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Viral Conjunctivitis.病毒性结膜炎。
Viruses. 2023 Mar 4;15(3):676. doi: 10.3390/v15030676.
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Epidemiological Investigation and Risk Factor Analysis of Acute Hemorrhagic Conjunctivitis in Huangshi Port District, Huangshi City.黄石港区急性出血性结膜炎的流行病学调查及危险因素分析。
Comput Math Methods Med. 2022 May 2;2022:3009589. doi: 10.1155/2022/3009589. eCollection 2022.
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Deep sequencing analysis of acute conjunctivitis in Burkina Faso, Africa.非洲布基纳法索急性结膜炎的深度测序分析。
Int Health. 2023 Jan 3;15(1):101-103. doi: 10.1093/inthealth/ihac001.
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Keeping an eye on pink eye: a global conjunctivitis outbreak expert survey.关注红眼病:全球结膜炎暴发专家调查。
Int Health. 2022 Sep 7;14(5):542-544. doi: 10.1093/inthealth/ihab049.
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Efficacy of compartmentalization in controlling an adenovirus type 54 keratoconjunctivitis outbreak on Oki Island, Japan.日本大久野岛采用分区隔离控制 54 型腺病毒结膜炎暴发的效果。
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Indian J Ophthalmol. 2020 May;68(5):732-736. doi: 10.4103/ijo.IJO_626_20.
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Management of Adenoviral Keratoconjunctivitis: Challenges and Solutions.腺病毒性角结膜炎的管理:挑战与解决方案
Clin Ophthalmol. 2020 Mar 17;14:837-852. doi: 10.2147/OPTH.S207976. eCollection 2020.
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