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因娱乐性使用氯胺酮导致的气性坏疽和败血症。

Gas necrosis and sepsis due to recreational ketamine use.

作者信息

Bezerra Alexandre Sacchetti, Vazquez Carla Maria Pasquareli, Guilherme Ana Carolina Troise, Rodrigues Ana Beatriz Retamero, Crivillari Murillo Barbosa, Queiroz Wladimir

机构信息

Faculdade de Medicina do ABC, Santo André, São Paulo, Brazil.

Hospital Israelita Albert Einstein, São Paulo, São Paulo, Brazil.

出版信息

Rev Inst Med Trop Sao Paulo. 2025 Feb 7;67:e9. doi: 10.1590/S1678-9946202567009. eCollection 2025.

Abstract

Although ketamine is an FDA-approved drug, its mechanism of action is not fully understood. Currently, there is an increase in its recreational use, causing irreparable social and physical damage. We report the case of a musician who developed sepsis due to gas necrosis in his arm after using veterinary ketamine purchased via the internet. Despite the amputation recommendation, it was possible to save the arm and preserve motor and sensory function. The scientific community, as well as the police and the government, must ponder the prescription, efficacy and safety of ketamine for medical treatments.

摘要

尽管氯胺酮是一种经美国食品药品监督管理局(FDA)批准的药物,但其作用机制尚未完全明确。目前,氯胺酮的娱乐性使用呈上升趋势,造成了无法弥补的社会和身体损害。我们报告了一名音乐家的病例,他通过互联网购买兽用氯胺酮后,手臂因气体坏疽而发生败血症。尽管有截肢的建议,但最终保住了手臂,并保留了运动和感觉功能。科学界、警方和政府必须认真思考氯胺酮用于医疗治疗时的处方、疗效和安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca7/11808713/f0e5fcbc7c1c/1678-9946-rimtsp-67-S1678-9946202567009-gf01.jpg

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