Gelyi Emmanuel K, Azaare John, Bonso Nana Kobea, Kpordoxah Mary Rachael, Aninanya Gifty Apiung
Department of Social and Behavioural Sciences, School of Public Health, University for Development Studies, Tamale, Ghana.
Department of Health Services, Policy Planning, Management and Economics, School of Public Health, University for Development Studies, Tamale, Ghana.
PLoS One. 2025 Feb 12;20(2):e0318662. doi: 10.1371/journal.pone.0318662. eCollection 2025.
Ghana faced acute COVID-19 vaccine uptake rejection after the rollout of the initial dose, thus, posing a risk of not reaching herd immunity as necessary to curb the spread of the novel coronavirus disease.
In this study, we analysed the impact of perceptions of the COVID-19 infection on COVID-19 vaccine uptake among healthcare workers in the Mampong district of Ghana.
The study was conducted between April 2022 and June 2023 and interviewed 260 respondents using a closed-ended electronic questionnaire in a Google form format. We then analysed for association using a composite outcome response of healthcare workers in Ghana using a multiple logistics regression model. The alpha value was set at p < 0.05 for statistical significance employing statistical software, IBM Statistical Package for the Social Sciences software. The analysis adjusted for independent covariates using respondent medical history, COVID-19 infection status, and sociodemographic characteristics.
Out of the total respondents, 219 (84.2%) took at least one shot of a COVID-19 vaccine. Of those who took a vaccine, 61.9% took AstraZeneca, followed by Johnson and Johnson (8.5%) and Pfizer BioNTech (6.2%). Vaccine uptake was significantly associated with positive previous vaccination history (p < 0.001), perceived vaccine safety (p < 0.001), perceived seriousness of COVID-19 infection (p < 0.008), and trust in COVID-19 vaccine based on recommendations by experts (p < 0.015).
Previous vaccination history and perceived factors such as vaccine safety, the seriousness of the COVID-19 infection, perceived risk of infection, and trust in expert recommendations influenced vaccine uptake among healthcare workers in Ghana.
加纳在首次接种新冠疫苗后，面临着对疫苗接种的强烈抵制，因此，存在无法达到群体免疫以遏制新型冠状病毒疾病传播的风险。
在本研究中，我们分析了对新冠感染的认知对加纳曼蓬区医护人员新冠疫苗接种率的影响。
该研究于2022年4月至2023年6月期间进行，使用谷歌表单格式的封闭式电子问卷对260名受访者进行了访谈。然后，我们使用多元逻辑回归模型，对加纳医护人员的综合结果反应进行关联分析。使用IBM社会科学统计软件包统计软件，将α值设定为p < 0.05以确定统计学显著性。分析针对独立协变量进行了调整，使用受访者的病史、新冠感染状况和社会人口特征。
在所有受访者中，219人（84.2%）至少接种了一剂新冠疫苗。在接种疫苗的人中，61.9%接种了阿斯利康疫苗，其次是强生疫苗（8.5%）和辉瑞生物科技疫苗（6.2%）。疫苗接种率与之前的阳性接种史（p < 0.001）、感知到的疫苗安全性（p < 0.001）、对新冠感染严重性的感知（p < 0.008）以及基于专家建议对新冠疫苗的信任（p < 0.015）显著相关。
之前的接种史以及诸如疫苗安全性、新冠感染的严重性、感知到的感染风险和对专家建议的信任等感知因素，影响了加纳医护人员的疫苗接种率。
